Madrigal Pharmaceuticals (MDGL) Financials: Revenue & Earnings
$9.89B
Market Cap
-33.96
P/E
75.33
Forward P/E
64
Score
MDGL price $427.93 -12.40 -2.82%
Stocklytics score rationale: value 48, quality 44, growth 100.
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 180133000 | 958403000 |
Madrigal Pharmaceuticals, Inc. is a biopharmaceutical company in the clinical development phase, concentrating its efforts on discovering and commercializing innovative treatments for cardiovascular, metabolic, and liver disorders. Its most advanced drug candidate, resmetirom, functions as a liver-targeted selective thyroid hormone receptor-ß agonist, currently undergoing late-stage (Phase III) clinical trials for…
MDGL fair value $309.78. Price $427.93. Price is 38% above fair value.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
Calculated with a 10-year free-cash-flow discount. Starting free cash flow 250.96M. Growth 20.00%. When analyst earnings forecasts are available, free cash flow in those years is forecast earnings times the company's usual conversion of earnings into free cash flow, kept between 60% and 130%. Years with fewer than 3 analyst estimates are left out. Growth then fades in a straight line to terminal growth by year 10, starting from the last well-covered year's growth, or from the pace across those years when the final year slows sharply, kept between 0% and 20%. Without those forecasts, year-1 growth is analyst revenue growth for the next full fiscal year, or 5-year historical revenue growth when that forecast is missing, held for five years, then fading in a straight line to terminal growth by year 10. Terminal growth 3.00%. Discount rate 10.00%. Beta is kept between 0.8 and 2.0, which on its own would make the discount rate 8.7% to 15.3%. The rate is then capped at 12%. A cap is used because a discount above 12% pushes higher-beta stocks further from the price. The discount rate stays at least 5 percentage points above terminal growth. Shares 23.10M. Net debt 155.67M. The earnings value is next-12-months earnings per share, or trailing earnings when that forecast is missing, times the stock's own 10-year median P/E, kept between 8 and 40. Fewer than five years of history uses the sector's typical P/E. Fair value is the average of the cash-flow value and the earnings value when both exist. Model uncertainty is high when fair value is more than 60% from the price, or when most of the cash-flow value sits after year 10.
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-11-03 | — | -0.86 | — | 404.17M |
| 2026-07-30 | -1.99 | -2.68 | 364.30M | 352.13M |
| 2026-05-06 | -3.25 | -3.61 | 311.34M | 301.05M |
| 2026-02-19 | -2.57 | 0.04 | 321.10M | 312.51M |
| 2025-11-04 | -5.08 | -2.04 | 287.27M | 244.96M |
| 2025-08-05 | -1.90 | -3.48 | 212.80M | 243.47M |
| 2025-05-01 | -3.32 | -3.62 | 137.25M | 158.93M |
| 2025-02-26 | -2.71 | -4.32 | 103.32M | 97.81M |
| 2024-10-31 | -4.92 | -6.94 | 62.17M | 92.53M |
| 2024-08-07 | -7.10 | -7.55 | 14.64M | 3.90M |
| 2024-05-07 | -7.38 | -6.06 | — | 3.90M |
| 2024-02-28 | -5.68 | -5.32 | 770.00K | — |
| 2023-11-06 | -5.34 | -4.78 | — | — |
| 2023-08-08 | -4.69 | -4.47 | — | — |
| 2023-05-09 | -4.23 | -4.98 | — | — |
| 2023-02-23 | -4.98 | -4.41 | — | — |
| 2022-11-03 | -4.75 | -4.05 | — | — |
| 2022-08-04 | -4.14 | -3.76 | — | — |
| 2022-05-09 | -3.36 | -3.75 | — | — |
| 2022-02-24 | -3.78 | -3.92 | — | — |
| 2021-11-04 | -3.79 | -3.89 | — | — |
| 2021-08-05 | -3.72 | -3.55 | — | — |
| 2021-05-06 | -3.32 | -3.78 | — | — |
| 2021-02-25 | -3.82 | -3.82 | — | — |
| 2020-11-05 | -3.75 | -3.35 | — | 4.83M |
| 2020-08-06 | -3.18 | -2.42 | — | 4.34M |
| 2020-05-07 | -2.34 | -1.94 | — | — |
| 2020-02-26 | -1.80 | -1.56 | — | 4.62M |
| 2019-11-06 | -1.39 | -1.36 | — | 5.19M |
| 2019-08-07 | -1.28 | -1.08 | — | 6.67M |
| 2019-05-08 | -0.98 | -0.93 | — | 5.69M |
| 2019-02-27 | -0.75 | -0.75 | — | — |
| 2018-11-06 | -0.56 | -0.54 | — | — |
| 2018-08-07 | -0.45 | -0.56 | — | — |
| 2018-05-08 | -0.45 | -0.75 | — | — |
| 2018-03-13 | -0.67 | -0.68 | — | — |
| 2017-11-09 | -0.68 | -0.84 | — | — |
| 2017-08-10 | -0.69 | -0.60 | — | 1.41M |
| 2017-05-11 | -0.50 | -1.39 | — | — |
| 2017-04-03 | -0.67 | — | — | — |
Yield 0.00%. Payout ratio 0.00%. Frequency —.
Safety score 37/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. No dividend history was found. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| No data yet. | ||||
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-09-11 | Sibold William John | Sell | 60 | $533.09 | 31.99K |
| 2026-09-11 | Sibold William John | Sell | 106 | $534.06 | 56.61K |
| 2026-09-11 | Sibold William John | Sell | 218 | $535.94 | 116.84K |
| 2026-09-11 | Sibold William John | Sell | 160 | $537.62 | 86.02K |
| 2026-09-11 | Sibold William John | Sell | 687 | $540.59 | 371.38K |
| 2026-09-11 | Sibold William John | Sell | 368 | $541.64 | 199.32K |
| 2026-09-11 | Sibold William John | Sell | 1.20K | $542.60 | 652.21K |
| 2026-09-11 | Sibold William John | Sell | 1.54K | $544.02 | 837.25K |
| 2026-09-11 | Sibold William John | Sell | 761 | $544.83 | 414.62K |
| 2026-09-11 | Sibold William John | Sell | 120 | $546.38 | 65.57K |
| 2026-09-09 | Sibold William John | Sell | 131 | $527.88 | 69.15K |
| 2026-09-09 | Sibold William John | Sell | 347 | $529.27 | 183.66K |
| 2026-09-09 | Sibold William John | Sell | 522 | $530.23 | 276.78K |
| 2026-09-09 | Sibold William John | Sell | 368 | $531.99 | 195.77K |
| 2026-09-09 | Sibold William John | Sell | 512 | $533.09 | 272.94K |
| 2026-09-09 | Sibold William John | Sell | 396 | $534.20 | 211.54K |
| 2026-09-09 | Sibold William John | Sell | 644 | $535.27 | 344.72K |
| 2026-09-09 | Sibold William John | Sell | 1.04K | $536.11 | 557.56K |
| 2026-09-09 | Sibold William John | Sell | 640 | $537.17 | 343.79K |
| 2026-09-09 | Sibold William John | Sell | 520 | $538.30 | 279.91K |
| 2026-09-09 | Sibold William John | Sell | 215 | $539.03 | 115.89K |
| 2026-09-09 | Sibold William John | Sell | 505 | $540.19 | 272.80K |
| 2026-09-09 | Sibold William John | Sell | 362 | $541.65 | 196.08K |
| 2026-09-09 | Sibold William John | Sell | 160 | $542.55 | 86.81K |
| 2026-08-17 | Kelley Shannon T | Sell | 664 | $514.97 | 341.94K |
| 2026-08-15 | REED JOHN C | Buy | 1.08K | $507.56 | 547.15K |
| 2026-08-15 | REED JOHN C | Buy | 647 | — | — |
| 2026-08-11 | REED JOHN C | Other | 0 | — | — |
| 2026-07-20 | Sibold William John | Sell | 140 | $542.75 | 75.98K |
| 2026-07-20 | Sibold William John | Sell | 110 | $543.79 | 59.82K |
| 2026-07-20 | Sibold William John | Sell | 545 | $544.71 | 296.87K |
| 2026-07-20 | Sibold William John | Sell | 275 | $545.71 | 150.07K |
| 2026-07-20 | Sibold William John | Sell | 269 | $547.08 | 147.16K |
| 2026-07-20 | Sibold William John | Sell | 680 | $547.70 | 372.43K |
| 2026-07-20 | Sibold William John | Sell | 47 | $548.87 | 25.80K |
| 2026-07-20 | Sibold William John | Sell | 153 | $550.01 | 84.15K |
| 2026-07-20 | Sibold William John | Sell | 1 | $550.72 | 551 |
| 2026-07-20 | Sibold William John | Sell | 280 | $555.05 | 155.41K |
| 2026-07-17 | Sibold William John | Buy | 50.00K | — | — |
| 2026-07-17 | Sibold William John | Sell | 50.00K | — | — |
| 2026-06-17 | Taub Rebecca | Buy | 454 | — | — |
| 2026-06-17 | Taub Rebecca | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | Levy Richard S | Buy | 454 | — | — |
| 2026-06-17 | Levy Richard S | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | FOUSE JACQUALYN A | Buy | 454 | — | — |
| 2026-06-17 | FOUSE JACQUALYN A | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | Daly James M | Buy | 454 | — | — |
| 2026-06-17 | Daly James M | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | Brennan Daniel J. | Buy | 404 | — | — |
| 2026-06-17 | Brennan Daniel J. | Buy | 681 | $499.86 | 340.40K |
| 2026-06-17 | BAKER BROS. ADVISORS LP | Buy | 908 | — | — |
| 2026-06-17 | BAKER BROS. ADVISORS LP | Buy | 908 | — | — |
| 2026-06-17 | BAKER BROS. ADVISORS LP | Buy | 1.53K | $499.86 | 765.79K |
| 2026-06-01 | Soergel David | Sell | 1.04K | $495.74 | 516.56K |
| 2026-05-22 | Levy Richard S | Sell | 40 | $506.68 | 20.27K |
| 2026-05-22 | Levy Richard S | Sell | 320 | $508.24 | 162.64K |
| 2026-05-22 | Levy Richard S | Sell | 151 | $510.36 | 77.06K |
| 2026-05-22 | Levy Richard S | Sell | 610 | $511.40 | 311.95K |
| 2026-05-22 | Levy Richard S | Sell | 439 | $512.50 | 224.99K |
| 2026-05-22 | Levy Richard S | Sell | 40 | $512.97 | 20.52K |
| 2026-05-22 | Levy Richard S | Sell | 343 | $514.67 | 176.53K |
| 2026-05-22 | Levy Richard S | Sell | 657 | $515.92 | 338.96K |
| 2026-05-22 | Levy Richard S | Sell | 723 | $516.87 | 373.69K |
| 2026-05-22 | Levy Richard S | Sell | 1.50K | $517.59 | 774.84K |
| 2026-05-22 | Levy Richard S | Sell | 782 | $518.76 | 405.67K |
| 2026-05-22 | Levy Richard S | Sell | 80 | $519.98 | 41.60K |
| 2026-05-18 | Soergel David | Sell | 844 | $515.90 | 435.42K |
| 2026-03-06 | Dier Mardi | Sell | 646 | $431.94 | 279.03K |
| 2026-03-06 | Dier Mardi | Sell | 40 | $425.08 | 17.00K |
| 2026-03-06 | Dier Mardi | Sell | 420 | $426.86 | 179.28K |
| 2026-03-06 | Dier Mardi | Sell | 80 | $427.85 | 34.23K |
| 2026-03-06 | Dier Mardi | Sell | 160 | $429.00 | 68.64K |
| 2026-03-06 | Dier Mardi | Sell | 40 | $429.58 | 17.18K |
| 2026-03-06 | Dier Mardi | Sell | 120 | $430.90 | 51.71K |
| 2026-03-06 | Dier Mardi | Sell | 116 | $432.56 | 50.18K |
| 2026-03-06 | Dier Mardi | Sell | 160 | $434.20 | 69.47K |
| 2026-03-06 | Dier Mardi | Sell | 80 | $435.31 | 34.83K |
| 2026-03-06 | Dier Mardi | Sell | 80 | $436.69 | 34.94K |
| 2026-03-06 | Dier Mardi | Sell | 40 | $437.65 | 17.51K |
| 2026-03-06 | Sibold William John | Sell | 1.66K | $431.94 | 718.32K |
| 2026-03-06 | Kelley Shannon T | Sell | 360 | $431.94 | 155.50K |
| 2026-03-06 | Huntsman Carole | Sell | 419 | $431.94 | 180.98K |
| 2026-03-06 | Taub Rebecca | Sell | 491 | $431.94 | 212.08K |
| 2026-03-04 | Dier Mardi | Buy | 5.21K | — | — |
| 2026-03-04 | Dier Mardi | Buy | 6.52K | $434.80 | 2.83M |
| 2026-03-04 | Sibold William John | Buy | 14.99K | — | — |
| 2026-03-04 | Sibold William John | Buy | 18.74K | $434.80 | 8.15M |
| 2026-03-04 | Kelley Shannon T | Buy | 4.02K | — | — |
| 2026-03-04 | Kelley Shannon T | Buy | 5.02K | $434.80 | 2.18M |
| 2026-03-04 | Huntsman Carole | Buy | 3.99K | — | — |
| 2026-03-04 | Huntsman Carole | Buy | 4.99K | $434.80 | 2.17M |
| 2026-03-04 | Soergel David | Buy | 4.37K | — | — |
| 2026-03-04 | Soergel David | Buy | 5.47K | $434.80 | 2.38M |
| 2026-03-02 | Dier Mardi | Sell | 1.18K | $427.21 | 505.39K |
| 2026-02-23 | Levy Richard S | Buy | 2.50K | $7.36 | 18.40K |
| 2026-02-23 | Levy Richard S | Sell | 2.50K | $7.36 | 18.40K |
| 2026-01-26 | Levy Richard S | Buy | 4.00K | $16.46 | 65.84K |
| 2026-01-26 | Levy Richard S | Sell | 4.00K | $16.46 | 65.84K |
| 2026-01-26 | Huntsman Carole | Sell | 340 | $492.42 | 167.42K |
| 2026-01-26 | Huntsman Carole | Sell | 570 | $494.59 | 281.92K |
Latest filed quarter: Q2 2026.
Institutions holding: 439, holders +31 vs prior quarter. Ownership 81.57%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 2.14M | 1.43K | +0.07% | 1.15B |
| RTW INVESTMENTS, LP | 1.99M | 0 | 0.00% | 1.07B |
| JUPITER TOPCO LLC | 1.94M | 1.94M | New | 1.04B |
| AVORO CAPITAL ADVISORS LLC | 1.83M | 15.15K | +0.83% | 984.41M |
| PAULSON & CO. INC. | 1.34M | -52.17K | -3.75% | 719.52M |
| BLACKROCK, INC. | 1.20M | -359.19K | -23.03% | 644.75M |
| VANGUARD CAPITAL MANAGEMENT LLC | 835.67K | 8.52K | +1.03% | 448.71M |
| WELLINGTON MANAGEMENT GROUP LLP | 825.71K | 130.76K | +18.81% | 443.37M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 781.73K | -59.41K | -7.06% | 419.75M |
| STATE STREET CORP | 527.06K | -82.47K | -13.53% | 283.00M |
| CITADEL ADVISORS LLC | 507.23K | 470.93K | +1297.34% | 272.36M |
| UBS GROUP AG | 401.71K | 283.93K | +241.07% | 215.70M |
| GEODE CAPITAL MANAGEMENT, LLC | 374.88K | -80.99K | -17.77% | 201.34M |
| FMR LLC | 356.20K | -155.53K | -30.39% | 191.26M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 324.12K | -16.40K | -4.82% | 174.04M |
| INVESCO LTD. | 301.44K | -28.08K | -8.52% | 161.86M |
| ARMISTICE CAPITAL, LLC | 288.00K | 23.42K | +8.85% | 154.64M |
| LORD, ABBETT & CO. LLC | 281.50K | 38.77K | +15.97% | 151.15M |
| GOLDMAN SACHS GROUP INC | 246.28K | -31.09K | -11.21% | 132.24M |
| POLAR CAPITAL HOLDINGS PLC | 244.27K | -45.04K | -15.57% | 131.16M |
| AMERIPRISE FINANCIAL INC | 231.21K | 133.02K | +135.49% | 124.15M |
| NORGES BANK | 213.89K | 213.89K | New | 114.85M |
| ARTISAN PARTNERS LIMITED PARTNERSHIP | 210.21K | 26.66K | +14.53% | 112.87M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 209.80K | 187.58K | +844.36% | 112.65M |
| PICTET ASSET MANAGEMENT HOLDING SA | 192.90K | 5.66K | +3.02% | 103.49M |
Madrigal Pharmaceuticals, Inc. (MDGL) trades at $427.93, with a market cap of $9.89B and a trailing P/E of -33.96. Revenue below is the annual history on file. It describes what the business has already reported. It is not a forecast and it is not a recommendation.
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 180133000 | 958403000 |
Insights · Dividends · Forecast · Financials · Learn
$9.89B
Market Cap
-33.96
P/E
75.33
Forward P/E
64
Score