Amylyx Pharmaceuticals (AMLX) Stock Insights
$3.52B
Market Cap
-18.84
P/E
12.72
Forward P/E
66
Score
AMLX price $28.07 -0.23 -0.81%
Stocklytics score rationale: value 49, quality 48, growth 100.
| 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|
| 1426000 | 650000 | 0 | 22230000 | 380786000 | 87371000 | 0 |
Amylyx Pharmaceuticals, Inc. operates as a clinical-stage biopharmaceutical firm, primarily focused on creating therapies for amyotrophic lateral sclerosis (ALS) and various other neurodegenerative conditions. A key asset in its developmental pipeline is AMX0035, a proprietary dual UPR-Bax apoptosis inhibitor. This compound, which integrates sodium phenylbutyrate and taurursodiol, is under investigation for treating…
AMLX fair value $86.34. Price $28.07. Price is 67% below fair value.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
Model uncertainty high for this stock
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-11-05 | — | -0.38 | — | 59.43K |
| 2026-08-06 | -0.39 | -0.36 | — | — |
| 2026-05-07 | -0.37 | -0.34 | — | — |
| 2026-03-03 | -0.30 | -0.31 | — | -52.00K |
| 2025-11-06 | -0.37 | -0.43 | — | 52.00K |
| 2025-08-07 | -0.46 | -0.44 | — | — |
| 2025-05-08 | -0.42 | -0.45 | — | — |
| 2025-03-04 | -0.55 | -0.49 | 665.00K | — |
| 2024-11-07 | -1.07 | -0.60 | 416.00K | 31.57M |
| 2024-08-08 | -0.73 | -0.38 | 1.02M | 10.66M |
| 2024-05-10 | -0.46 | -0.00 | 88.60M | 98.35M |
| 2024-02-22 | 0.07 | 0.23 | 108.45M | 106.96M |
| 2023-11-09 | 0.30 | 0.44 | 102.69M | 107.85M |
| 2023-08-10 | 0.31 | 0.10 | 98.22M | 92.11M |
| 2023-05-11 | 0.02 | -0.24 | 71.43M | 87.61M |
| 2023-03-13 | -0.65 | -0.77 | 21.89M | 58.99M |
| 2022-11-10 | -0.92 | -0.97 | 345.00K | 83.33K |
| 2022-08-11 | -0.93 | -0.92 | — | 125.00K |
| 2022-05-12 | -0.93 | -0.75 | — | 83.33K |
| 2022-03-30 | -4.15 | -0.64 | — | — |
| 2022-01-10 | -0.42 | — | 285.00K | — |
| 2021-06-30 | -0.48 | — | — | — |
| 2021-03-31 | -0.32 | — | — | — |
| 2020-12-31 | -0.19 | — | 350.00K | — |
Yield 0.00%. Payout ratio 0.00%. Frequency Quarterly.
Safety score 43/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. Dividend history is short. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| 2018-03-28 | $0.42 | — | 2018-04-02 | Quarterly |
| 2017-12-28 | $0.36 | — | 2018-01-02 | Quarterly |
| 2017-09-28 | $0.24 | — | 2017-10-02 | Quarterly |
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-10-05 | MILNE GEORGE M JR | Sell | 30.00K | $27.70 | 830.90K |
| 2026-09-10 | Bedrosian Camille L | Sell | 7.95K | $32.21 | 256.00K |
| 2026-09-10 | Bedrosian Camille L | Sell | 2.08K | $33.09 | 68.86K |
| 2026-09-10 | FRATES JAMES M | Sell | 9.77K | $32.27 | 315.19K |
| 2026-09-10 | FRATES JAMES M | Sell | 1.04K | $33.23 | 34.63K |
| 2026-09-10 | Mazzariello Gina | Sell | 9.53K | $32.46 | 309.14K |
| 2026-09-10 | Mazzariello Gina | Sell | 11 | $33.34 | 367 |
| 2026-09-10 | Klee Justin B. | Sell | 29.02K | $32.13 | 932.55K |
| 2026-09-10 | Klee Justin B. | Sell | 1.44K | $33.16 | 47.71K |
| 2026-09-10 | Cohen Joshua B | Sell | 29.55K | $32.16 | 950.04K |
| 2026-09-10 | Cohen Joshua B | Sell | 919 | $33.15 | 30.46K |
| 2026-08-31 | Firestone Karen | Buy | 25.00K | $5.05 | 126.25K |
| 2026-08-31 | Firestone Karen | Buy | 25.00K | $1.76 | 44.00K |
| 2026-08-31 | Firestone Karen | Sell | 25.00K | $1.76 | 44.00K |
| 2026-08-31 | Firestone Karen | Sell | 25.00K | $5.05 | 126.25K |
| 2026-08-18 | FRATES JAMES M | Buy | 22.81K | — | — |
| 2026-08-18 | Klee Justin B. | Buy | 60.04K | — | — |
| 2026-08-18 | Mazzariello Gina | Buy | 21.28K | — | — |
| 2026-08-18 | Bedrosian Camille L | Buy | 22.81K | — | — |
| 2026-08-18 | Cohen Joshua B | Buy | 60.04K | — | — |
| 2026-07-10 | Mazzariello Gina | Sell | 15.00K | $17.61 | 264.12K |
| 2026-07-09 | Mazzariello Gina | Sell | 15.00K | $18.32 | 274.75K |
| 2026-06-04 | Zeiher Bernhardt G | Buy | 24.37K | $14.31 | 348.76K |
| 2026-06-04 | Firestone Karen | Buy | 24.37K | $14.31 | 348.76K |
| 2026-06-04 | Quimi Daphne | Buy | 24.37K | $14.31 | 348.76K |
| 2026-06-04 | MILNE GEORGE M JR | Buy | 24.37K | $14.31 | 348.76K |
| 2026-06-04 | FONTEYNE PAUL R. | Buy | 24.37K | $14.31 | 348.76K |
| 2026-05-21 | Firestone Karen | Buy | 3.80K | $13.51 | 51.34K |
| 2026-03-05 | Cohen Joshua B | Buy | 248.87K | — | — |
| 2026-03-05 | Cohen Joshua B | Buy | 373.30K | $14.10 | 5.26M |
| 2026-03-05 | Mazzariello Gina | Buy | 74.66K | — | — |
| 2026-03-05 | Mazzariello Gina | Buy | 111.99K | $14.10 | 1.58M |
| 2026-03-05 | FRATES JAMES M | Buy | 95.99K | — | — |
| 2026-03-05 | FRATES JAMES M | Buy | 143.99K | $14.10 | 2.03M |
| 2026-03-05 | Klee Justin B. | Buy | 248.87K | — | — |
| 2026-03-05 | Klee Justin B. | Buy | 373.30K | $14.10 | 5.26M |
| 2026-03-05 | Bedrosian Camille L | Buy | 95.99K | — | — |
| 2026-03-05 | Bedrosian Camille L | Buy | 143.99K | $14.10 | 2.03M |
| 2026-03-02 | Klee Justin B. | Sell | 29.28K | $14.47 | 423.76K |
| 2026-03-02 | Cohen Joshua B | Sell | 29.28K | $14.48 | 424.12K |
| 2026-03-02 | Bedrosian Camille L | Sell | 6.46K | $14.58 | 94.21K |
| 2026-03-02 | FRATES JAMES M | Sell | 7.91K | $14.52 | 114.85K |
| 2026-03-02 | Mazzariello Gina | Sell | 6.84K | $14.52 | 99.38K |
| 2026-02-23 | Mazzariello Gina | Sell | 3.42K | $14.14 | 48.35K |
| 2026-02-02 | FRATES JAMES M | Sell | 3.56K | $14.65 | 52.10K |
| 2026-02-02 | Cohen Joshua B | Sell | 15.50K | $14.68 | 227.59K |
| 2026-02-02 | Mazzariello Gina | Sell | 3.45K | $14.65 | 50.52K |
| 2026-02-02 | Klee Justin B. | Sell | 15.50K | $14.69 | 227.62K |
| 2026-01-16 | Cohen Joshua B | Buy | 2.82K | $7.57 | 21.33K |
| 2026-01-16 | Cohen Joshua B | Sell | 1.97K | $13.83 | 27.30K |
| 2026-01-16 | Cohen Joshua B | Sell | 2.82K | $7.57 | 21.33K |
| 2026-01-16 | Klee Justin B. | Buy | 2.85K | $7.57 | 21.55K |
| 2026-01-16 | Klee Justin B. | Sell | 2.00K | $13.89 | 27.70K |
| 2026-01-16 | Klee Justin B. | Sell | 2.85K | $7.57 | 21.55K |
| 2026-01-15 | Cohen Joshua B | Buy | 197.18K | $7.57 | 1.49M |
| 2026-01-15 | Cohen Joshua B | Sell | 136.19K | $13.59 | 1.85M |
| 2026-01-15 | Cohen Joshua B | Sell | 197.18K | $7.57 | 1.49M |
| 2026-01-15 | Klee Justin B. | Buy | 197.15K | $7.57 | 1.49M |
| 2026-01-15 | Klee Justin B. | Sell | 136.19K | $13.58 | 1.85M |
| 2026-01-15 | Klee Justin B. | Sell | 197.15K | $7.57 | 1.49M |
| 2026-01-12 | MILNE GEORGE M JR | Sell | 17.78K | — | — |
| 2026-01-06 | FRATES JAMES M | Sell | 3.33K | $11.11 | 36.95K |
| 2026-01-06 | Cohen Joshua B | Sell | 7.71K | $11.09 | 85.60K |
| 2026-01-06 | Klee Justin B. | Sell | 7.71K | $11.09 | 85.59K |
| 2025-12-23 | Firestone Karen | Buy | 8.10K | $12.45 | 100.84K |
| 2025-12-01 | Bedrosian Camille L | Sell | 6.58K | $14.35 | 94.42K |
| 2025-09-30 | Klee Justin B. | Sell | 29.77K | $14.37 | 427.95K |
| 2025-09-30 | Klee Justin B. | Sell | 200 | $15.01 | 3.00K |
| 2025-09-30 | Mazzariello Gina | Sell | 8.83K | $14.58 | 128.67K |
| 2025-09-30 | FRATES JAMES M | Sell | 10.56K | $14.65 | 154.65K |
| 2025-09-30 | Cohen Joshua B | Sell | 29.73K | $14.34 | 426.47K |
| 2025-09-30 | Cohen Joshua B | Sell | 200 | $15.00 | 3.00K |
| 2025-09-30 | Bedrosian Camille L | Sell | 12.04K | $14.58 | 175.52K |
| 2025-08-13 | Mazzariello Gina | Sell | 15.00K | $8.34 | 125.05K |
| 2025-08-12 | Mazzariello Gina | Sell | 15.00K | $8.07 | 121.10K |
| 2025-06-05 | FONTEYNE PAUL R. | Buy | 25.00K | $5.05 | 126.25K |
| 2025-06-05 | Firestone Karen | Buy | 25.00K | $5.05 | 126.25K |
| 2025-06-05 | Quimi Daphne | Buy | 25.00K | $5.05 | 126.25K |
| 2025-06-05 | MILNE GEORGE M JR | Buy | 25.00K | $5.05 | 126.25K |
| 2025-06-05 | Zeiher Bernhardt G | Buy | 25.00K | $5.05 | 126.25K |
| 2025-05-22 | Mazzariello Gina | Sell | 1.00K | — | — |
| 2025-03-31 | FRATES JAMES M | Sell | 10.90K | $3.47 | 37.81K |
| 2025-03-31 | Bedrosian Camille L | Sell | 12.43K | $3.47 | 43.08K |
| 2025-03-31 | Mazzariello Gina | Sell | 9.19K | $3.48 | 31.95K |
| 2025-03-31 | Cohen Joshua B | Sell | 21.49K | $3.47 | 74.48K |
| 2025-03-31 | Klee Justin B. | Sell | 21.49K | $3.46 | 74.45K |
| 2025-03-20 | Zeiher Bernhardt G | Buy | 10.00K | $3.70 | 37.01K |
| 2025-03-06 | Mazzariello Gina | Buy | 63.85K | — | — |
| 2025-03-06 | Mazzariello Gina | Buy | 95.78K | $3.61 | 345.75K |
| 2025-03-06 | Bedrosian Camille L | Buy | 68.42K | — | — |
| 2025-03-06 | Bedrosian Camille L | Buy | 102.63K | $3.61 | 370.49K |
| 2025-03-06 | Klee Justin B. | Buy | 180.12K | — | — |
| 2025-03-06 | Klee Justin B. | Buy | 270.18K | $3.61 | 975.34K |
| 2025-03-06 | Cohen Joshua B | Buy | 180.12K | — | — |
| 2025-03-06 | Cohen Joshua B | Buy | 270.18K | $3.61 | 975.34K |
| 2025-03-06 | FRATES JAMES M | Buy | 68.42K | — | — |
| 2025-03-06 | FRATES JAMES M | Buy | 102.63K | $3.61 | 370.49K |
| 2025-03-03 | Klee Justin B. | Sell | 4.59K | $3.15 | 14.48K |
| 2025-03-03 | Cohen Joshua B | Sell | 4.59K | $3.17 | 14.55K |
| 2025-03-03 | Mazzariello Gina | Sell | 1.61K | $3.12 | 5.02K |
Latest filed quarter: Q2 2026.
Institutions holding: 223, holders +42 vs prior quarter. Ownership 104.66%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| FMR LLC | 16.73M | 97.37K | +0.59% | 300.43M |
| BLACKROCK, INC. | 8.83M | -1.75K | -0.02% | 158.53M |
| PERCEPTIVE ADVISORS LLC | 8.33M | 50.00K | +0.60% | 149.69M |
| TCG CROSSOVER MANAGEMENT, LLC | 6.24M | 0 | 0.00% | 112.14M |
| COMMODORE CAPITAL LP | 5.65M | 0 | 0.00% | 101.47M |
| JUPITER TOPCO LLC | 5.24M | 5.24M | New | 94.01M |
| SATURN V CAPITAL MANAGEMENT LP | 4.62M | 274.22K | +6.30% | 83.05M |
| VANGUARD CAPITAL MANAGEMENT LLC | 4.22M | 82.65K | +2.00% | 75.87M |
| MORGAN STANLEY | 3.13M | 955.26K | +43.91% | 56.23M |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 3.04M | 49.82K | +1.67% | 54.54M |
| FIRST LIGHT ASSET MANAGEMENT, LLC | 3.02M | -167.39K | -5.25% | 54.30M |
| FRANKLIN TEMPLETON INC | 2.95M | 688.66K | +30.45% | 52.99M |
| GOLDMAN SACHS GROUP INC | 2.86M | 232.25K | +8.84% | 51.33M |
| STATE STREET CORP | 2.60M | 240.18K | +10.16% | 46.76M |
| GEODE CAPITAL MANAGEMENT, LLC | 2.34M | 124.38K | +5.63% | 41.95M |
| JPMORGAN CHASE & CO | 1.86M | 1.70M | +1067.24% | 34.92M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.90M | -1.66M | -46.64% | 34.12M |
| SIREN, L.L.C. | 1.48M | 250.59K | +20.37% | 26.59M |
| EVENTIDE ASSET MANAGEMENT, LLC | 1.33M | -186.42K | -12.31% | 23.84M |
| 683 CAPITAL MANAGEMENT, LLC | 1.28M | 1.18M | +1224.55% | 22.98M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1.06M | 116.75K | +12.36% | 19.07M |
| ALYESKA INVESTMENT GROUP, L.P. | 1.05M | 1.05M | New | 18.91M |
| ALMITAS CAPITAL LLC | 974.88K | -1.15M | -54.07% | 17.51M |
| DIMENSIONAL FUND ADVISORS LP | 902.46K | -729 | -0.08% | 16.22M |
| JONES HILL CAPITAL LP | 894.06K | -704.74K | -44.08% | 16.06M |
Insights · Dividends · Forecast · Financials · Learn
$3.52B
Market Cap
-18.84
P/E
12.72
Forward P/E
66
Score