Karyopharm Therapeutics (KPTI) Stock Insights
$17.39M
Market Cap
-0.02
P/E
1.06
Forward P/E
—
Score
KPTI price $0.77 +0.29 +59.73%
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 154000 | 1605000 | 30336000 | 40893000 | 108085000 | 209819000 | 157074000 | 146033000 | 145237000 | 146067000 |
Karyopharm Therapeutics Inc. is a pharmaceutical company that has already brought products to market, focusing on identifying, advancing, and selling medications designed to disrupt nuclear export pathways. These drugs are primarily aimed at treating cancer and various other illnesses. The company's strategy involves researching, creating, and marketing innovative Selective Inhibitor of Nuclear Export (SINE)…
KPTI fair value $28.15. Price $0.77. Price is 97% below fair value.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
Model uncertainty high for this stock
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-11-02 | — | -0.95 | — | 33.54M |
| 2026-08-13 | -2.32 | -1.37 | 33.43M | 32.19M |
| 2026-05-14 | -1.24 | -1.45 | 35.07M | 31.40M |
| 2026-02-12 | -5.68 | -2.26 | 34.08M | 35.10M |
| 2025-11-03 | -3.82 | -3.47 | 44.04M | 42.06M |
| 2025-08-11 | -4.32 | -3.80 | 37.93M | 38.03M |
| 2025-05-12 | -2.77 | -4.21 | 30.02M | 35.12M |
| 2025-02-19 | -3.60 | -0.25 | 30.54M | 35.67M |
| 2024-11-05 | -3.90 | -3.94 | 38.78M | 37.92M |
| 2024-08-06 | -3.00 | -4.35 | 42.79M | 36.21M |
| 2024-05-08 | -4.80 | -4.95 | 33.13M | 34.48M |
| 2024-02-29 | -5.40 | -0.31 | 33.75M | 35.40M |
| 2023-11-02 | -4.50 | -4.20 | 36.01M | 37.27M |
| 2023-08-02 | -4.35 | -5.10 | 37.58M | 35.67M |
| 2023-05-04 | -4.50 | -0.37 | 38.70M | 36.32M |
| 2023-02-15 | -0.43 | -0.35 | 33.58M | 34.43M |
| 2022-11-03 | -0.45 | -8.40 | 36.15M | 34.83M |
| 2022-08-04 | -0.62 | -9.45 | 39.68M | 35.96M |
| 2022-05-05 | -0.53 | -9.45 | 47.67M | 34.41M |
| 2022-02-08 | 0.46 | -6.00 | 126.27M | 52.71M |
| 2021-11-03 | -0.69 | -10.19 | 37.69M | 25.80M |
| 2021-08-05 | -0.71 | -10.79 | 22.60M | 22.60M |
| 2021-05-03 | -0.77 | -10.49 | 23.26M | 26.57M |
| 2021-02-11 | -0.59 | -8.70 | 35.10M | 27.37M |
| 2020-11-02 | -10.94 | -10.94 | 21.33M | 21.04M |
| 2020-08-04 | -9.45 | -8.55 | 33.51M | 30.85M |
| 2020-05-05 | -11.69 | -10.49 | 18.14M | 16.05M |
| 2020-02-13 | -11.39 | -0.67 | 18.10M | 15.95M |
| 2019-11-04 | -10.04 | -0.83 | 13.15M | 16.29M |
| 2019-08-06 | -10.64 | -0.98 | 9.49M | 13.10M |
| 2019-05-09 | -16.34 | -0.87 | 155.00K | 123.72K |
| 2019-02-28 | -14.39 | -13.19 | 206.00K | 182.40K |
| 2018-11-08 | -11.84 | -13.19 | 239.00K | 269.25K |
| 2018-08-07 | -9.00 | -11.39 | 19.89M | 26.85M |
| 2018-05-10 | -11.69 | -10.04 | 10.00M | 7.95M |
| 2018-03-15 | -11.99 | -9.90 | 1.53M | 1.25M |
| 2017-11-02 | -9.75 | -0.64 | — | 69.91K |
| 2017-08-08 | -9.60 | -0.66 | 3.00K | 3.05K |
| 2017-05-04 | -10.64 | -0.67 | 68.00K | 64.17K |
| 2017-03-16 | -0.65 | -9.75 | 47.00K | 47.72K |
Yield 0.00%. Payout ratio 0.00%. Frequency —.
Safety score 37/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. No dividend history was found. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| No data yet. | ||||
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-10-16 | Abate Kristin | Sell | 4.79K | $0.34 | 1.65K |
| 2026-10-01 | Abate Kristin | Sell | 378 | $1.19 | 450 |
| 2026-09-01 | Abate Kristin | Sell | 19 | $2.02 | 38 |
| 2026-07-28 | Poulton Stuart | Sell | 189 | $7.10 | 1.34K |
| 2026-05-21 | Oliger Christy J. | Buy | 15.51K | — | — |
| 2026-05-21 | PAKIANATHAN DEEPIKA | Buy | 15.51K | — | — |
| 2026-05-21 | Schor Chen | Buy | 15.51K | — | — |
| 2026-05-21 | Su Zhen | Buy | 15.51K | — | — |
| 2026-05-21 | BOHLIN GAREN G | Buy | 15.51K | — | — |
| 2026-05-21 | Greene Barry E | Buy | 15.51K | — | — |
| 2026-05-14 | Poulton Stuart | Sell | 403 | $9.50 | 3.83K |
| 2026-05-14 | Rangwala Reshma | Sell | 408 | $9.50 | 3.88K |
| 2026-05-14 | Cheng Sohanya Roshan | Sell | 324 | $9.50 | 3.08K |
| 2026-05-14 | Abate Kristin | Sell | 53 | $9.50 | 504 |
| 2026-05-14 | Paulson Richard A. | Sell | 2.20K | $9.50 | 20.93K |
| 2026-05-14 | Mano Michael | Sell | 266 | $9.50 | 2.53K |
| 2026-05-13 | Poulton Stuart | Buy | 896 | — | — |
| 2026-05-13 | Rangwala Reshma | Buy | 947 | — | — |
| 2026-05-13 | Cheng Sohanya Roshan | Buy | 947 | — | — |
| 2026-05-13 | Abate Kristin | Buy | 121 | — | — |
| 2026-05-13 | Paulson Richard A. | Buy | 4.92K | — | — |
| 2026-05-13 | Mano Michael | Buy | 700 | — | — |
| 2026-04-21 | Rangwala Reshma | Sell | 449 | $8.94 | 4.01K |
| 2026-03-02 | Mano Michael | Sell | 3.53K | $9.41 | 33.18K |
| 2026-03-02 | Cheng Sohanya Roshan | Sell | 4.60K | $9.41 | 43.32K |
| 2026-03-02 | Rangwala Reshma | Sell | 5.07K | $9.41 | 47.67K |
| 2026-03-02 | Paulson Richard A. | Sell | 12.36K | $9.41 | 116.31K |
| 2026-03-02 | Poulton Stuart | Sell | 5.10K | $9.41 | 48.00K |
| 2026-02-17 | Poulton Stuart | Sell | 378 | $8.63 | 3.26K |
| 2026-02-05 | Paulson Richard A. | Buy | 81.06K | — | — |
| 2026-02-03 | Macomber Lori | Sell | 1.63K | $6.30 | 10.24K |
| 2026-01-31 | Cheng Sohanya Roshan | Buy | 32.41K | — | — |
| 2026-01-31 | Rangwala Reshma | Buy | 32.41K | — | — |
| 2026-01-31 | Macomber Lori | Buy | 32.41K | — | — |
| 2026-01-31 | Mano Michael | Buy | 32.41K | — | — |
| 2026-01-31 | Poulton Stuart | Buy | 32.41K | — | — |
| 2026-01-28 | Abate Kristin | Sell | 50 | $7.03 | 352 |
| 2026-01-27 | Abate Kristin | Buy | 92 | — | — |
| 2026-01-21 | Abate Kristin | Sell | 265 | $5.96 | 1.58K |
| 2025-10-15 | Abate Kristin | Buy | 12.80K | — | — |
| 2025-10-15 | Poulton Stuart | Buy | 39.68K | — | — |
| 2025-10-15 | Mano Michael | Buy | 43.65K | — | — |
| 2025-10-15 | Paulson Richard A. | Buy | 114.28K | — | — |
| 2025-10-15 | Cheng Sohanya Roshan | Buy | 43.65K | — | — |
| 2025-10-15 | Macomber Lori | Buy | 43.65K | — | — |
| 2025-10-01 | Abate Kristin | Sell | 362 | $6.30 | 2.28K |
| 2025-09-15 | Paulson Richard A. | Sell | 1.26K | $6.43 | 8.08K |
| 2025-09-15 | Mano Michael | Sell | 234 | $6.43 | 1.50K |
| 2025-09-15 | Poulton Stuart | Sell | 401 | $6.43 | 2.58K |
| 2025-09-15 | Rangwala Reshma | Sell | 408 | $6.43 | 2.62K |
| 2025-09-15 | Cheng Sohanya Roshan | Sell | 325 | $6.43 | 2.09K |
| 2025-09-15 | Abate Kristin | Sell | 23 | $6.43 | 148 |
| 2025-09-12 | Paulson Richard A. | Buy | 2.80K | — | — |
| 2025-09-12 | Mano Michael | Buy | 612 | — | — |
| 2025-09-12 | Poulton Stuart | Buy | 888 | — | — |
| 2025-09-12 | Rangwala Reshma | Buy | 945 | — | — |
| 2025-09-12 | Cheng Sohanya Roshan | Buy | 945 | — | — |
| 2025-09-12 | Abate Kristin | Buy | 46 | — | — |
| 2025-09-03 | Abate Kristin | Sell | 12 | $6.78 | 81 |
| 2025-07-29 | Poulton Stuart | Sell | 191 | $4.37 | 835 |
| 2025-07-22 | Abate Kristin | Sell | 238 | $4.00 | 952 |
| 2025-05-28 | Su Zhen | Buy | 4.60K | $4.48 | 20.61K |
| 2025-05-28 | PAKIANATHAN DEEPIKA | Buy | 4.60K | $4.48 | 20.61K |
| 2025-05-28 | Oliger Christy J. | Buy | 4.60K | $4.48 | 20.61K |
| 2025-05-28 | Mirza Mansoor Raza | Buy | 4.60K | $4.48 | 20.61K |
| 2025-05-28 | Greene Barry E | Buy | 4.60K | $4.48 | 20.61K |
| 2025-05-28 | Schor Chen | Buy | 4.60K | $4.48 | 20.61K |
| 2025-05-28 | BOHLIN GAREN G | Buy | 4.60K | $4.48 | 20.61K |
| 2025-05-06 | Paulson Richard A. | Sell | 236 | $7.12 | 1.68K |
| 2025-04-23 | Rangwala Reshma | Sell | 419 | $6.17 | 2.59K |
| 2025-04-04 | Paulson Richard A. | Sell | 245 | $3.74 | 916 |
| 2025-03-04 | Mano Michael | Sell | 2.79K | $6.29 | 17.57K |
| 2025-02-28 | Cheng Sohanya Roshan | Buy | 4.58K | — | — |
| 2025-02-28 | Cheng Sohanya Roshan | Buy | 5.42K | — | — |
| 2025-02-28 | Cheng Sohanya Roshan | Buy | 10.83K | $7.95 | 86.12K |
| 2025-02-28 | Cheng Sohanya Roshan | Buy | 9.17K | $7.95 | 72.87K |
| 2025-02-28 | Rangwala Reshma | Buy | 4.58K | — | — |
| 2025-02-28 | Rangwala Reshma | Buy | 5.42K | — | — |
| 2025-02-28 | Rangwala Reshma | Buy | 10.83K | $7.95 | 86.12K |
| 2025-02-28 | Rangwala Reshma | Buy | 9.17K | $7.95 | 72.87K |
| 2025-02-28 | Poulton Stuart | Buy | 4.58K | — | — |
| 2025-02-28 | Poulton Stuart | Buy | 5.00K | — | — |
| 2025-02-28 | Poulton Stuart | Buy | 10.00K | $7.95 | 79.50K |
| 2025-02-28 | Poulton Stuart | Buy | 9.17K | $7.95 | 72.87K |
| 2025-02-28 | Abate Kristin | Buy | 933 | — | — |
| 2025-02-28 | Abate Kristin | Buy | 1.87K | $7.95 | 14.83K |
| 2025-02-28 | Paulson Richard A. | Buy | 20.00K | — | — |
| 2025-02-28 | Paulson Richard A. | Buy | 40.00K | $7.95 | 318.00K |
| 2025-02-28 | Mano Michael | Buy | 2.25K | — | — |
| 2025-02-28 | Mano Michael | Buy | 3.33K | — | — |
| 2025-02-28 | Mano Michael | Buy | 6.67K | $7.95 | 52.99K |
| 2025-02-28 | Mano Michael | Buy | 4.50K | $7.95 | 35.77K |
| 2025-02-18 | Poulton Stuart | Sell | 5.91K | $0.63 | 3.73K |
| 2025-02-04 | Paulson Richard A. | Sell | 4.10K | $0.65 | 2.66K |
| 2025-01-31 | Macomber Lori | Buy | 650.00K | $0.62 | 404.37K |
| 2025-01-31 | Macomber Lori | Buy | 160.00K | — | — |
| 2025-01-06 | Paulson Richard A. | Sell | 4.05K | $0.78 | 3.18K |
| 2025-01-03 | Macomber Lori | Other | 0 | — | — |
| 2024-12-04 | Paulson Richard A. | Sell | 3.62K | $0.81 | 2.93K |
| 2024-11-06 | Abate Kristin | Other | 0 | — | — |
Latest filed quarter: Q2 2026.
Institutions holding: 112, holders +12 vs prior quarter. Ownership 73.18%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 1.92M | 0 | 0.00% | 18.73M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.52M | -285.00K | -15.78% | 14.86M |
| ACORN CAPITAL ADVISORS, LLC | 1.52M | 1.23M | +427.44% | 14.83M |
| GOLDMAN SACHS GROUP INC | 1.42M | 477.08K | +50.35% | 13.92M |
| BLACKROCK, INC. | 1.42M | 1.17M | +479.34% | 13.86M |
| VANGUARD CAPITAL MANAGEMENT LLC | 958.98K | 219.23K | +29.64% | 9.37M |
| CATALIO CAPITAL MANAGEMENT, LP | 940.86K | 43.15K | +4.81% | 9.19M |
| AVIDITY PARTNERS MANAGEMENT LP | 924.49K | 460.75K | +99.35% | 9.03M |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 786.31K | -755.78K | -49.01% | 7.68M |
| TWO SIGMA INVESTMENTS, LP | 695.26K | 544.03K | +359.73% | 6.79M |
| KALEHUA CAPITAL MANAGEMENT LLC | 685.64K | 685.64K | New | 6.70M |
| NEA MANAGEMENT COMPANY, LLC | 576.78K | 576.78K | New | 5.64M |
| GEODE CAPITAL MANAGEMENT, LLC | 531.23K | 325.10K | +157.71% | 5.19M |
| GHISALLO CAPITAL MANAGEMENT LLC | 500.00K | 500.00K | New | 4.88M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 484.80K | 460.66K | +1908.45% | 4.74M |
| SOLEUS CAPITAL MANAGEMENT, L.P. | 440.00K | 0 | 0.00% | 4.30M |
| UBS GROUP AG | 353.55K | 159.53K | +82.22% | 3.45M |
| STATE STREET CORP | 325.99K | 245.25K | +303.74% | 3.18M |
| AFFINITY ASSET ADVISORS, LLC | 312.50K | -187.50K | -37.50% | 3.05M |
| BREVAN HOWARD CAPITAL MANAGEMENT LP | 309.82K | 97.45K | +45.89% | 3.03M |
| MILLENNIUM MANAGEMENT LLC | 305.68K | 214.68K | +235.91% | 2.99M |
| BOXER CAPITAL MANAGEMENT, LLC | 302.54K | 0 | 0.00% | 2.96M |
| DAVIDSON KEMPNER CAPITAL MANAGEMENT LP | 300.00K | 0 | 0.00% | 2.93M |
| ACADIAN ASSET MANAGEMENT LLC | 299.00K | 50.04K | +20.10% | 2.92M |
| SILVERARC CAPITAL MANAGEMENT, LLC | 297.46K | 297.46K | New | 2.91M |
Insights · Dividends · Forecast · Financials · Learn
$17.39M
Market Cap
-0.02
P/E
1.06
Forward P/E
—
Score