Protagonist Therapeutics (PTGX) Stock Insights
$9.20B
Market Cap
115.20
P/E
30.28
Forward P/E
55
Score
PTGX price $142.14 +1.02 +0.72%
Stocklytics score rationale: value 15, quality 65, growth 86.
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 0 | 20063000 | 30925000 | 231000 | 28628000 | 27357000 | 26581000 | 60000000 | 434433000 | 46016000 |
Protagonist Therapeutics, Inc. is a biopharmaceutical firm dedicated to discovering and advancing peptide-based therapies. Their research primarily focuses on treatments for hematological and blood conditions, as well as inflammatory and immune-mediated disorders. The company's pipeline features rusfertide (PTG-300), an injectable hepcidin mimetic currently undergoing Phase II clinical trials for the management of…
PTGX fair value $78.42. Price $142.14. Price is 81% above fair value.
Above fair value, around its usual premium.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
Model uncertainty high for this stock
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-11-05 | — | 2.50 | — | 238.48M |
| 2026-08-05 | 2.29 | 2.23 | 213.47M | 198.66M |
| 2026-05-05 | 0.05 | -0.65 | 56.37M | 11.70M |
| 2026-02-25 | -0.69 | -0.53 | 7.44M | 8.74M |
| 2025-11-06 | -0.62 | -0.59 | 4.71M | 14.92M |
| 2025-08-06 | -0.55 | -0.53 | 5.55M | 8.43M |
| 2025-05-06 | -0.19 | -0.50 | 28.32M | 6.56M |
| 2025-02-21 | 1.98 | 0.06 | 170.64M | 81.01M |
| 2024-11-07 | -0.54 | -0.59 | 4.67M | 38.81M |
| 2024-08-06 | -0.50 | -0.50 | 4.17M | 8.00M |
| 2024-05-07 | 3.26 | 1.19 | 254.95M | 120.00M |
| 2024-02-27 | 0.44 | 0.03 | 60.00M | 40.00M |
| 2023-11-02 | -0.58 | -0.68 | — | 38.33M |
| 2023-08-03 | -0.68 | -0.65 | — | 8.33M |
| 2023-05-04 | -0.67 | -0.69 | — | 2.00M |
| 2023-03-15 | -0.69 | -0.67 | — | 5.00M |
| 2022-11-08 | -0.64 | -0.94 | — | — |
| 2022-08-04 | -0.84 | -0.99 | 859.00K | 460.00K |
| 2022-05-04 | -0.43 | -0.67 | 25.72M | 21.18M |
| 2022-02-28 | -0.77 | -0.79 | 8.62M | 5.07M |
| 2021-11-03 | -0.70 | -0.67 | 10.29M | 2.03M |
| 2021-08-04 | -0.69 | -0.62 | 2.27M | 5.17M |
| 2021-05-04 | -0.54 | -0.57 | 6.19M | 3.12M |
| 2021-03-10 | -0.48 | -0.47 | 5.65M | — |
| 2020-11-04 | -0.21 | -0.61 | 13.11M | 9.44M |
| 2020-08-06 | -0.59 | -0.57 | 6.22M | 6.01M |
| 2020-05-07 | -0.72 | -0.64 | 3.65M | 3.50M |
| 2020-03-10 | -0.63 | -0.64 | 2.72M | 2.81M |
| 2019-11-06 | -0.61 | -0.75 | 4.14M | 4.82M |
| 2019-08-07 | -1.18 | -0.27 | 8.19M | 1.94M |
| 2019-05-08 | -0.58 | -0.65 | 1.56M | 1.59M |
| 2019-03-12 | -0.57 | -0.42 | 2.35M | 1.94M |
| 2018-11-06 | -0.38 | -0.40 | 6.12M | 5.96M |
| 2018-08-07 | -0.41 | -0.30 | 11.67M | 9.97M |
| 2018-05-09 | -0.36 | -0.24 | 10.78M | 8.68M |
| 2018-03-07 | -0.15 | -0.36 | 11.28M | 26.32M |
| 2017-11-06 | -0.29 | -0.95 | 8.78M | 21.50M |
| 2017-08-08 | -0.89 | -0.92 | — | — |
| 2017-05-10 | -0.84 | -0.64 | — | — |
| 2017-03-07 | -0.67 | -0.52 | — | — |
Yield 0.00%. Payout ratio 0.00%. Frequency —.
Safety score 37/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. No dividend history was found. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| No data yet. | ||||
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-09-30 | Ali Asif | Buy | 5.31K | $12.17 | 64.65K |
| 2026-09-30 | Ali Asif | Buy | 15.65K | $19.19 | 300.32K |
| 2026-09-30 | Ali Asif | Sell | 12.60K | $141.77 | 1.79M |
| 2026-09-30 | Ali Asif | Buy | 28.44K | $23.42 | 666.02K |
| 2026-09-30 | Ali Asif | Buy | 9.23K | $38.98 | 359.75K |
| 2026-09-30 | Ali Asif | Sell | 46.03K | $141.78 | 6.53M |
| 2026-09-30 | Ali Asif | Sell | 15.65K | $19.19 | 300.32K |
| 2026-09-30 | Ali Asif | Sell | 28.44K | $23.42 | 666.02K |
| 2026-09-30 | Ali Asif | Sell | 9.23K | $38.98 | 359.75K |
| 2026-09-30 | Ali Asif | Sell | 5.31K | $12.17 | 64.65K |
| 2026-09-10 | PATEL DINESH V PH D | Buy | 7.28K | $21.58 | 157.06K |
| 2026-09-10 | PATEL DINESH V PH D | Sell | 7.28K | $144.10 | 1.05M |
| 2026-09-10 | PATEL DINESH V PH D | Sell | 7.28K | $21.58 | 157.06K |
| 2026-09-09 | PATEL DINESH V PH D | Buy | 63.55K | $21.58 | 1.37M |
| 2026-09-09 | PATEL DINESH V PH D | Sell | 63.55K | $146.18 | 9.29M |
| 2026-09-09 | PATEL DINESH V PH D | Sell | 63.55K | $21.58 | 1.37M |
| 2026-09-08 | PATEL DINESH V PH D | Buy | 54.17K | $21.58 | 1.17M |
| 2026-09-08 | PATEL DINESH V PH D | Sell | 54.17K | $145.87 | 7.90M |
| 2026-09-08 | PATEL DINESH V PH D | Sell | 54.17K | $21.58 | 1.17M |
| 2026-09-03 | PATEL DINESH V PH D | Sell | 510 | — | — |
| 2026-08-11 | PATEL DINESH V PH D | Buy | 34.24K | $21.58 | 738.88K |
| 2026-08-11 | PATEL DINESH V PH D | Sell | 34.24K | $148.52 | 5.09M |
| 2026-08-11 | PATEL DINESH V PH D | Sell | 34.24K | $21.58 | 738.88K |
| 2026-08-10 | PATEL DINESH V PH D | Buy | 65.76K | $21.58 | 1.42M |
| 2026-08-10 | PATEL DINESH V PH D | Sell | 65.76K | $149.11 | 9.81M |
| 2026-08-10 | PATEL DINESH V PH D | Sell | 65.76K | $21.58 | 1.42M |
| 2026-06-23 | Waddill William D. | Buy | 9.00K | $16.54 | 148.86K |
| 2026-06-23 | Waddill William D. | Sell | 9.00K | $117.94 | 1.06M |
| 2026-06-23 | Waddill William D. | Sell | 9.00K | $16.54 | 148.86K |
| 2026-06-10 | Waddill William D. | Buy | 6.00K | $16.54 | 99.24K |
| 2026-06-10 | Waddill William D. | Buy | 3.00K | $11.80 | 35.40K |
| 2026-06-10 | Waddill William D. | Sell | 6.00K | $16.54 | 99.24K |
| 2026-06-10 | Waddill William D. | Sell | 9.00K | $107.68 | 969.12K |
| 2026-06-10 | Waddill William D. | Sell | 3.00K | $11.80 | 35.40K |
| 2026-05-29 | Waddill William D. | Buy | 9.00K | $11.80 | 106.20K |
| 2026-05-29 | Waddill William D. | Sell | 9.00K | $99.64 | 896.76K |
| 2026-05-29 | Waddill William D. | Sell | 9.00K | $11.80 | 106.20K |
| 2026-05-12 | PATEL DINESH V PH D | Buy | 75.00K | $21.58 | 1.62M |
| 2026-05-12 | PATEL DINESH V PH D | Sell | 75.00K | $100.12 | 7.51M |
| 2026-05-12 | PATEL DINESH V PH D | Sell | 75.00K | $21.58 | 1.62M |
| 2026-05-08 | Giraudo Bryan | Sell | 5.13K | $100.00 | 513.00K |
| 2026-05-08 | Giraudo Bryan | Sell | 6.00K | $100.00 | 600.00K |
| 2026-05-07 | Giraudo Bryan | Buy | 12.00K | $6.98 | 83.76K |
| 2026-05-07 | Giraudo Bryan | Buy | 24.00K | $6.45 | 154.80K |
| 2026-05-07 | Giraudo Bryan | Sell | 36.00K | $100.14 | 3.61M |
| 2026-05-07 | Giraudo Bryan | Sell | 12.00K | $100.07 | 1.20M |
| 2026-05-07 | Giraudo Bryan | Sell | 12.00K | $6.98 | 83.76K |
| 2026-05-07 | Giraudo Bryan | Sell | 24.00K | $6.45 | 154.80K |
| 2026-04-23 | PATEL DINESH V PH D | Sell | 1.46K | — | — |
| 2026-04-20 | Ali Asif | Sell | 1.75K | $105.47 | 184.57K |
| 2026-03-26 | MOLINA ARTURO MD | Buy | 15.00K | $8.04 | 120.60K |
| 2026-03-26 | MOLINA ARTURO MD | Sell | 15.00K | $104.79 | 1.57M |
| 2026-03-26 | MOLINA ARTURO MD | Sell | 15.00K | $8.04 | 120.60K |
| 2026-03-26 | SELICK HAROLD E | Buy | 24.00K | $12.88 | 309.12K |
| 2026-03-26 | SELICK HAROLD E | Sell | 24.00K | $105.00 | 2.52M |
| 2026-03-26 | SELICK HAROLD E | Sell | 24.00K | $12.88 | 309.12K |
| 2026-03-26 | Ali Asif | Buy | 5.26K | $12.17 | 64.08K |
| 2026-03-26 | Ali Asif | Buy | 19.50K | $19.19 | 374.20K |
| 2026-03-26 | Ali Asif | Sell | 24.77K | $104.24 | 2.58M |
| 2026-03-26 | Ali Asif | Sell | 19.50K | $19.19 | 374.20K |
| 2026-03-26 | Ali Asif | Sell | 5.26K | $12.17 | 64.08K |
| 2026-03-25 | PATEL DINESH V PH D | Buy | 54.64K | $8.58 | 468.82K |
| 2026-03-25 | PATEL DINESH V PH D | Sell | 54.64K | $101.00 | 5.52M |
| 2026-03-25 | PATEL DINESH V PH D | Sell | 54.64K | $8.58 | 468.82K |
| 2026-03-24 | PATEL DINESH V PH D | Buy | 59 | $8.58 | 506 |
| 2026-03-24 | PATEL DINESH V PH D | Sell | 59 | $8.58 | 506 |
| 2026-03-23 | PATEL DINESH V PH D | Sell | 50.00K | — | — |
| 2026-02-17 | Williams Lewis T | Buy | 18.00K | $10.84 | 195.12K |
| 2026-02-17 | Williams Lewis T | Sell | 18.00K | $82.42 | 1.48M |
| 2026-02-17 | Williams Lewis T | Buy | 18.00K | $10.84 | 195.12K |
| 2026-02-06 | Waddill William D. | Buy | 20.00K | $8.31 | 166.20K |
| 2026-02-06 | Waddill William D. | Sell | 20.00K | $83.68 | 1.67M |
| 2026-02-06 | Waddill William D. | Sell | 20.00K | $8.31 | 166.20K |
| 2026-01-27 | PATEL DINESH V PH D | Buy | 4.07K | $21.58 | 87.79K |
| 2026-01-27 | PATEL DINESH V PH D | Sell | 4.07K | $83.19 | 338.42K |
| 2026-01-27 | PATEL DINESH V PH D | Sell | 4.07K | $21.58 | 87.79K |
| 2026-01-27 | Ali Asif | Buy | 12.00K | $12.17 | 146.04K |
| 2026-01-27 | Ali Asif | Buy | 16.00K | $19.19 | 307.04K |
| 2026-01-27 | Ali Asif | Sell | 28.00K | $83.13 | 2.33M |
| 2026-01-27 | Ali Asif | Sell | 18.20K | $83.14 | 1.51M |
| 2026-01-27 | Ali Asif | Sell | 16.00K | $19.19 | 307.04K |
| 2026-01-27 | Ali Asif | Sell | 12.00K | $12.17 | 146.04K |
| 2026-01-27 | MOLINA ARTURO MD | Buy | 5.00K | $8.04 | 40.20K |
| 2026-01-27 | MOLINA ARTURO MD | Sell | 5.00K | $82.00 | 410.00K |
| 2026-01-27 | MOLINA ARTURO MD | Sell | 5.00K | $8.04 | 40.20K |
| 2026-01-26 | PATEL DINESH V PH D | Buy | 14.21K | $21.58 | 306.54K |
| 2026-01-26 | PATEL DINESH V PH D | Buy | 10.69K | $4.21 | 44.98K |
| 2026-01-26 | PATEL DINESH V PH D | Sell | 10.69K | $84.00 | 897.54K |
| 2026-01-26 | PATEL DINESH V PH D | Sell | 14.21K | $84.05 | 1.19M |
| 2026-01-26 | PATEL DINESH V PH D | Sell | 14.21K | $21.58 | 306.54K |
| 2026-01-26 | PATEL DINESH V PH D | Sell | 10.69K | $4.21 | 44.98K |
| 2026-01-26 | MOLINA ARTURO MD | Sell | 5.00K | $82.28 | 411.40K |
| 2026-01-26 | MOLINA ARTURO MD | Sell | 5.00K | $8.04 | 40.20K |
| 2026-01-23 | PATEL DINESH V PH D | Buy | 19.32K | $4.21 | 81.32K |
| 2026-01-23 | PATEL DINESH V PH D | Sell | 19.32K | $84.59 | 1.63M |
| 2026-01-23 | PATEL DINESH V PH D | Sell | 6.00K | — | — |
| 2026-01-23 | PATEL DINESH V PH D | Sell | 19.32K | $4.21 | 81.32K |
| 2026-01-23 | MOLINA ARTURO MD | Sell | 13.15K | $82.42 | 1.08M |
| 2026-01-20 | MOLINA ARTURO MD | Sell | 9.51K | $82.48 | 784.71K |
| 2026-01-20 | PATEL DINESH V PH D | Sell | 34.44K | $82.48 | 2.84M |
Latest filed quarter: Q2 2026.
Institutions holding: 358, holders +24 vs prior quarter. Ownership 115.84%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| BLACKROCK, INC. | 10.31M | 528.47K | +5.40% | 1.26B |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | 6.35M | 0 | 0.00% | 778.25M |
| RTW INVESTMENTS, LP | 5.06M | 2.12K | +0.04% | 620.40M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 3.63M | 148.09K | +4.25% | 444.88M |
| WELLINGTON MANAGEMENT GROUP LLP | 3.42M | -182.86K | -5.08% | 418.83M |
| UBS GROUP AG | 3.40M | -1.78M | -34.35% | 416.68M |
| STATE STREET CORP | 3.32M | 204.81K | +6.57% | 407.16M |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.85M | 47.50K | +1.69% | 349.77M |
| JOHNSON & JOHNSON | 2.45M | 0 | 0.00% | 300.22M |
| INVESCO LTD. | 2.34M | 176.00K | +8.13% | 286.92M |
| PRICE T ROWE ASSOCIATES INC /MD/ | 2.15M | 484.17K | +29.07% | 263.51M |
| JUPITER TOPCO LLC | 2.13M | 2.13M | New | 261.04M |
| GEODE CAPITAL MANAGEMENT, LLC | 1.74M | 71.84K | +4.30% | 213.48M |
| WOODLINE PARTNERS LP | 1.41M | 0 | 0.00% | 173.35M |
| BANK OF AMERICA CORP /DE/ | 1.32M | 29.06K | +2.24% | 162.36M |
| JENNISON ASSOCIATES LLC | 1.15M | 79.67K | +7.43% | 141.17M |
| PERCEPTIVE ADVISORS LLC | 981.88K | -249.00K | -20.23% | 120.36M |
| ADAR1 CAPITAL MANAGEMENT, LLC | 960.86K | -33.26K | -3.35% | 117.78M |
| MORGAN STANLEY | 905.99K | -112.23K | -11.02% | 111.06M |
| ALYESKA INVESTMENT GROUP, L.P. | 889.30K | 296.10K | +49.92% | 109.01M |
| HOOD RIVER CAPITAL MANAGEMENT LLC | 882.74K | 53.45K | +6.45% | 108.21M |
| GOLDMAN SACHS GROUP INC | 812.85K | 33.91K | +4.35% | 99.64M |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 731.05K | 10.12K | +1.40% | 89.61M |
| CLEARBRIDGE INVESTMENTS, LLC | 725.34K | 103.52K | +16.65% | 88.91M |
| FMR LLC | 672.19K | 10.19K | +1.54% | 82.40M |
| Period | Value |
|---|---|
| FY2019 | License And Collaborative Revenue: 200000.0 |
| FY2020 | Financial Service Other: 1500000.0, License And Collaborative Revenue: 28600000.0 |
| FY2021 | License and Collaboration Agreement: 18600000.0 |
| FY2024 | Development Services: 15300000.0 |
Insights · Dividends · Forecast · Financials · Learn
$9.20B
Market Cap
115.20
P/E
30.28
Forward P/E
55
Score