Syndax Pharmaceuticals (SNDX) Stock Insights
$1.28B
Market Cap
-5.32
P/E
40.78
Forward P/E
—
Score
SNDX price $14.32 +0.63 +4.60%
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 1220000 | 2108000 | 1517000 | 1517000 | 1517000 | 139709000 | 0 | 0 | 23680000 | 172352000 |
Syndax Pharmaceuticals, Inc. operates as a clinical-stage biopharmaceutical firm focused on developing innovative therapies for cancer. Among its leading investigational products are SNDX-5613, currently undergoing Phase 1/2 clinical assessment, which targets the Menin-mixed lineage leukemia 1 protein interaction for treating MLL-rearranged (MLLr) and nucleophosmin 1 mutant acute myeloid leukemia (NPM1c AML)…
SNDX fair value $15.93. Price $14.32. Price is 10% below fair value.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
Calculated with a 10-year free-cash-flow discount. Starting free cash flow 39.15M. Growth 20.00%. When analyst earnings forecasts are available, free cash flow in those years is forecast earnings times the company's usual conversion of earnings into free cash flow, kept between 60% and 130%. Years with fewer than 3 analyst estimates are left out. Growth then fades in a straight line to terminal growth by year 10, starting from the last well-covered year's growth, or from the pace across those years when the final year slows sharply, kept between 0% and 20%. Without those forecasts, year-1 growth is analyst revenue growth for the next full fiscal year, or 5-year historical revenue growth when that forecast is missing, held for five years, then fading in a straight line to terminal growth by year 10. Terminal growth 3.00%. Discount rate 8.70% (beta 0.8). Beta is kept between 0.8 and 2.0, which on its own would make the discount rate 8.7% to 15.3%. The rate is then capped at 12%. A cap is used because a discount above 12% pushes higher-beta stocks further from the price. The discount rate stays at least 5 percentage points above terminal growth. Shares 89.30M. Net debt 211.55M. The earnings value is next-12-months earnings per share, or trailing earnings when that forecast is missing, times the median P/E of the company's industry. That median uses listed stocks worth at least $10 billion with a positive P/E of 100 or below, and the industry needs at least eight of them. Otherwise the sector median is used when that group also has at least eight, then the market median of those large companies. The multiple used is the lower of that median and 1.25 times the stock's own 10-year median P/E, then kept between 8 and 30. If the stock has no 10-year median, the peer median is kept between 8 and 30. Fair value is the average of the cash-flow value and the earnings value when both exist. Card and credit companies use the earnings value only, because changes in customer receivables distort free cash flow. Model uncertainty is high when fair value is more than 60% from the price, or when most of the cash-flow value sits after year 10.
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-11-02 | — | -0.52 | — | 81.92M |
| 2026-08-04 | -0.55 | -0.45 | 72.79M | 79.37M |
| 2026-04-30 | -0.48 | -0.59 | 64.86M | 69.76M |
| 2026-02-26 | -0.78 | -0.58 | 68.73M | 64.30M |
| 2025-11-03 | -0.70 | -0.74 | 45.87M | 63.34M |
| 2025-08-04 | -0.83 | -1.00 | 37.96M | 45.65M |
| 2025-05-05 | -0.98 | -1.04 | 20.04M | 18.55M |
| 2025-03-03 | -1.10 | -1.08 | 7.68M | 12.79M |
| 2024-11-05 | -0.98 | -1.13 | 12.50M | 115.23M |
| 2024-08-01 | -0.80 | -0.91 | 3.50M | — |
| 2024-05-08 | -0.85 | -0.96 | — | — |
| 2024-02-27 | -1.00 | -0.99 | 536.00K | — |
| 2023-11-02 | -0.73 | -0.80 | — | — |
| 2023-08-03 | -0.64 | -0.73 | — | — |
| 2023-05-08 | -0.59 | -0.61 | — | 430.00K |
| 2023-02-28 | -0.62 | -0.64 | — | 1.33M |
| 2022-11-03 | -0.58 | -0.65 | — | 750.00K |
| 2022-08-08 | -0.62 | -0.65 | — | 1.38M |
| 2022-05-09 | -0.63 | -0.63 | — | 2.56M |
| 2022-03-01 | 1.81 | 0.28 | 126.58M | 6.29M |
| 2021-11-15 | -0.40 | -0.64 | 12.38M | 11.98M |
| 2021-08-09 | -0.44 | -0.74 | 379.00K | 379.00K |
| 2021-05-11 | -0.54 | -0.64 | 379.00K | 220.00K |
| 2021-03-08 | -0.44 | -0.43 | 380.00K | 240.00K |
| 2020-11-02 | -0.46 | -0.42 | 379.00K | 363.48K |
| 2020-08-06 | -0.42 | -0.47 | 379.00K | 406.07K |
| 2020-05-07 | -0.56 | -0.51 | 379.00K | 345.16K |
| 2020-03-03 | -0.44 | -0.46 | 380.00K | 361.77K |
| 2019-11-07 | -0.41 | -0.48 | 379.00K | 434.46K |
| 2019-08-07 | -0.47 | -0.44 | 379.00K | 346.74K |
| 2019-05-06 | -0.53 | -0.56 | 379.00K | 400.45K |
| 2019-03-07 | -0.70 | -0.68 | 380.00K | 362.76K |
| 2018-11-05 | -0.68 | -0.76 | 379.00K | 423.59K |
| 2018-08-07 | -0.74 | -0.91 | 379.00K | 445.58K |
| 2018-05-08 | -0.79 | -1.02 | 379.00K | 460.56K |
| 2018-03-05 | -0.80 | -0.85 | 1.19M | 1.16M |
| 2017-11-07 | -0.68 | -0.80 | 305.00K | 358.82K |
| 2017-08-10 | -0.70 | -0.79 | 305.00K | 361.64K |
| 2017-05-08 | -0.71 | -0.74 | 305.00K | 300.70K |
| 2017-03-02 | -0.59 | -0.77 | 305.00K | 377.37K |
Yield 0.00%. Payout ratio 0.00%. Frequency —.
Safety score 37/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. No dividend history was found. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| No data yet. | ||||
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-07-08 | Metzger Michael A | Buy | 32.38K | $6.38 | 206.55K |
| 2026-07-08 | Metzger Michael A | Sell | 32.38K | $24.24 | 784.78K |
| 2026-07-08 | Metzger Michael A | Buy | 32.38K | $6.38 | 206.55K |
| 2026-06-12 | Botwood Nicholas A.J. | Buy | 31.23K | $13.82 | 431.67K |
| 2026-06-12 | Botwood Nicholas A.J. | Sell | 31.23K | $18.14 | 566.60K |
| 2026-06-12 | Botwood Nicholas A.J. | Buy | 31.23K | $13.82 | 431.67K |
| 2026-06-11 | Botwood Nicholas A.J. | Buy | 22.52K | $13.82 | 311.16K |
| 2026-06-11 | Botwood Nicholas A.J. | Sell | 34.28K | $18.00 | 617.04K |
| 2026-06-01 | Goldan Keith A. | Sell | 1.18K | $18.99 | 22.35K |
| 2026-06-01 | Metzger Michael A | Sell | 6.85K | $18.99 | 130.02K |
| 2026-02-09 | Metzger Michael A | Sell | 17.16K | $21.03 | 360.82K |
| 2026-02-09 | Goldan Keith A. | Sell | 3.41K | $21.03 | 71.71K |
| 2026-02-06 | Metzger Michael A | Sell | 7.41K | $20.62 | 152.84K |
| 2026-02-06 | Goldan Keith A. | Sell | 2.08K | $20.62 | 42.93K |
| 2026-02-04 | Metzger Michael A | Buy | 144.60K | — | — |
| 2026-02-04 | Metzger Michael A | Buy | 440.00K | $20.43 | 8.99M |
| 2026-02-04 | Metzger Michael A | Buy | 73.00K | — | — |
| 2026-02-04 | Goldan Keith A. | Buy | 30.75K | — | — |
| 2026-02-04 | Goldan Keith A. | Buy | 118.00K | $20.43 | 2.41M |
| 2026-02-04 | Goldan Keith A. | Buy | 21.50K | — | — |
| 2026-02-04 | Jarrett Jennifer | Buy | 24.00K | — | — |
| 2026-02-04 | Huber Martin H. Jr. | Buy | 24.00K | — | — |
| 2026-02-04 | Botwood Nicholas A.J. | Buy | 144.70K | $20.43 | 2.96M |
| 2026-02-04 | Botwood Nicholas A.J. | Buy | 36.00K | — | — |
| 2026-02-04 | Botwood Nicholas A.J. | Buy | 24.00K | — | — |
| 2026-02-04 | Podlesak Dennis | Buy | 48.00K | — | — |
| 2026-02-04 | Rizo Aleksandra | Buy | 24.00K | — | — |
| 2026-02-04 | Katkin Keith | Buy | 24.00K | — | — |
| 2026-02-04 | Legault Pierre | Buy | 24.00K | — | — |
| 2026-01-30 | Goldan Keith A. | Buy | 1.22K | $8.48 | 10.34K |
| 2025-12-01 | Goldan Keith A. | Sell | 1.22K | — | — |
| 2025-09-08 | Metzger Michael A | Buy | 157.31K | $10.90 | 1.71M |
| 2025-09-08 | Metzger Michael A | Sell | 157.31K | $16.41 | 2.58M |
| 2025-09-08 | Metzger Michael A | Buy | 157.31K | $10.90 | 1.71M |
| 2025-08-18 | Podlesak Dennis | Buy | 19.20K | $7.20 | 138.24K |
| 2025-08-18 | Podlesak Dennis | Sell | 19.20K | $15.84 | 304.17K |
| 2025-08-18 | Podlesak Dennis | Sell | 19.20K | $7.20 | 138.24K |
| 2025-08-15 | Podlesak Dennis | Sell | 19.20K | $15.54 | 298.41K |
| 2025-08-14 | Podlesak Dennis | Sell | 19.20K | $14.19 | 272.52K |
| 2025-07-31 | Goldan Keith A. | Buy | 1.23K | $8.43 | 10.34K |
| 2025-07-16 | Goldan Keith A. | Sell | 1.30K | $9.29 | 12.03K |
| 2025-07-16 | Metzger Michael A | Sell | 7.53K | $9.29 | 69.95K |
| 2025-05-19 | Goldan Keith A. | Buy | 3.00K | — | — |
| 2025-05-19 | Huber Martin H. Jr. | Buy | 5.00K | $8.99 | 44.95K |
| 2025-05-19 | Katkin Keith | Buy | 10.00K | $9.11 | 91.12K |
| 2025-05-16 | Botwood Nicholas A.J. | Buy | 11.77K | $8.99 | 105.83K |
| 2025-05-12 | Botwood Nicholas A.J. | Other | 0 | — | — |
| 2025-05-12 | Botwood Nicholas A.J. | Other | 215.00K | $13.82 | 2.97M |
| 2025-03-14 | Metzger Michael A | Buy | 6.07K | $7.20 | 43.73K |
| 2025-03-14 | Metzger Michael A | Buy | 6.07K | $7.20 | 43.73K |
| 2025-03-04 | Metzger Michael A | Buy | 7.81K | $7.20 | 56.26K |
| 2025-03-04 | Metzger Michael A | Sell | 7.81K | $15.05 | 117.56K |
| 2025-03-04 | Metzger Michael A | Buy | 7.81K | $7.20 | 56.26K |
| 2025-02-10 | Goldan Keith A. | Sell | 3.78K | $15.50 | 58.56K |
| 2025-02-10 | Metzger Michael A | Sell | 13.29K | $15.50 | 206.02K |
| 2025-02-10 | Gallagher Neil | Sell | 4.62K | $15.50 | 71.60K |
| 2025-02-05 | Gallagher Neil | Buy | 110.50K | $14.65 | 1.62M |
| 2025-02-05 | Gallagher Neil | Buy | 23.40K | — | — |
| 2025-02-05 | Gallagher Neil | Buy | 18.50K | — | — |
| 2025-02-05 | Goldan Keith A. | Buy | 110.50K | $14.65 | 1.62M |
| 2025-02-05 | Goldan Keith A. | Buy | 23.40K | — | — |
| 2025-02-05 | Goldan Keith A. | Buy | 18.50K | — | — |
| 2025-02-05 | Metzger Michael A | Buy | 364.00K | $14.65 | 5.33M |
| 2025-02-05 | Metzger Michael A | Buy | 89.00K | — | — |
| 2025-02-05 | Metzger Michael A | Buy | 60.50K | — | — |
| 2025-02-05 | Podlesak Dennis | Buy | 50.00K | — | — |
| 2025-02-05 | Rizo Aleksandra | Buy | 25.00K | — | — |
| 2025-02-05 | Meury William | Buy | 25.00K | — | — |
| 2025-02-05 | Katkin Keith | Buy | 25.00K | — | — |
| 2025-02-05 | Jarrett Jennifer | Buy | 25.00K | — | — |
| 2025-02-05 | Huber Martin H. Jr. | Buy | 25.00K | — | — |
| 2025-02-05 | Legault Pierre | Buy | 25.00K | — | — |
| 2024-06-14 | Goldan Keith A. | Buy | 1.25K | $20.03 | 25.04K |
| 2024-05-15 | Rizo Aleksandra | Buy | 35.00K | $21.94 | 767.90K |
| 2024-05-15 | Rizo Aleksandra | Other | 0 | — | — |
| 2024-02-07 | Metzger Michael A | Buy | 214.50K | $22.28 | 4.78M |
| 2024-02-07 | Metzger Michael A | Buy | 39.00K | — | — |
| 2024-02-07 | Metzger Michael A | Buy | 107.25K | — | — |
| 2024-02-07 | Goldan Keith A. | Buy | 70.00K | $22.28 | 1.56M |
| 2024-02-07 | Goldan Keith A. | Buy | 11.70K | — | — |
| 2024-02-07 | Goldan Keith A. | Buy | 35.00K | — | — |
| 2024-02-07 | Gallagher Neil | Buy | 69.38K | $22.28 | 1.55M |
| 2024-02-07 | Gallagher Neil | Buy | 13.12K | — | — |
| 2024-02-07 | Gallagher Neil | Buy | 34.69K | — | — |
| 2024-02-07 | Huber Martin H. Jr. | Buy | 17.00K | — | — |
| 2024-02-07 | Jarrett Jennifer | Buy | 17.00K | — | — |
| 2024-02-07 | Katkin Keith | Buy | 17.00K | — | — |
| 2024-02-07 | Meury William | Buy | 17.00K | — | — |
| 2024-02-07 | Morrison Briggs | Buy | 17.00K | — | — |
| 2024-02-07 | Podlesak Dennis | Buy | 34.00K | — | — |
| 2024-02-07 | Legault Pierre | Buy | 17.00K | — | — |
| 2024-01-31 | Goldan Keith A. | Buy | 1.18K | $17.42 | 20.61K |
| 2023-08-09 | Morrison Briggs | Buy | 52.85K | $8.77 | 463.54K |
| 2023-08-09 | Morrison Briggs | Sell | 52.85K | $18.27 | 965.40K |
| 2023-08-09 | Morrison Briggs | Sell | 52.85K | $8.77 | 463.54K |
| 2023-08-02 | Meury William | Buy | 35.00K | $7.11 | 248.85K |
| 2023-08-02 | Meury William | Buy | 24.00K | $9.47 | 227.28K |
| 2023-08-02 | Meury William | Buy | 24.00K | $7.88 | 189.12K |
| 2023-08-02 | Meury William | Sell | 35.00K | $20.46 | 715.95K |
| 2023-08-02 | Meury William | Sell | 24.00K | $20.45 | 490.91K |
Latest filed quarter: Q2 2026.
Institutions holding: 254, holders -7 vs prior quarter. Ownership 122.39%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| BLACKROCK, INC. | 9.02M | 765.58K | +9.27% | 197.18M |
| KYNAM CAPITAL MANAGEMENT, LP | 8.05M | 0 | 0.00% | 175.99M |
| GOLDMAN SACHS GROUP INC | 5.86M | 864.48K | +17.30% | 128.13M |
| STATE STREET CORP | 5.66M | 1.23M | +27.73% | 123.69M |
| BANK OF AMERICA CORP /DE/ | 4.05M | -204.74K | -4.82% | 88.43M |
| VANGUARD CAPITAL MANAGEMENT LLC | 3.93M | 105.31K | +2.76% | 85.86M |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 3.78M | 0 | 0.00% | 82.63M |
| EVERSEPT PARTNERS, LP | 2.80M | -87.41K | -3.03% | 61.17M |
| GEODE CAPITAL MANAGEMENT, LLC | 2.58M | 427.08K | +19.80% | 56.50M |
| HOOD RIVER CAPITAL MANAGEMENT LLC | 2.56M | 209.99K | +8.92% | 56.06M |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 2.50M | 0 | 0.00% | 54.65M |
| FRANKLIN TEMPLETON INC | 2.29M | 136.42K | +6.34% | 49.98M |
| MILLENNIUM MANAGEMENT LLC | 2.05M | 1.85M | +929.43% | 44.90M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 1.92M | 184.66K | +10.63% | 42.01M |
| UBS GROUP AG | 1.89M | 740.09K | +64.15% | 41.40M |
| ELMIND CAPITAL, LP | 1.85M | 0 | 0.00% | 40.55M |
| BNP PARIBAS ASSET MANAGEMENT HOLDING S.A. | 1.79M | 57.63K | +3.33% | 39.13M |
| CANDRIAM S.C.A. | 1.70M | 770.71K | +83.29% | 37.04M |
| SOLEUS CAPITAL MANAGEMENT, L.P. | 1.63M | -98.87K | -5.73% | 35.59M |
| TWO SIGMA INVESTMENTS, LP | 1.58M | -1.47K | -0.09% | 34.50M |
| ORBIMED ADVISORS LLC | 1.54M | 579.70K | +60.24% | 33.71M |
| NUVEEN, LLC | 1.36M | -130.07K | -8.70% | 29.83M |
| MPM BIOIMPACT LLC | 1.33M | -7.21K | -0.54% | 29.15M |
| AISLING CAPITAL MANAGEMENT LP | 1.32M | 0 | 0.00% | 28.79M |
| WOODLINE PARTNERS LP | 1.25M | 0 | 0.00% | 27.34M |
Insights · Dividends · Forecast · Financials · Learn
$1.28B
Market Cap
-5.32
P/E
40.78
Forward P/E
—
Score