Spero Therapeutics (SPRO) Stock Insights
SPRO$1.17+0.03 +2.63%
$68.13M
Market Cap
7.64
P/E
1.56
Forward P/E
62
Score
Spero Therapeutics (SPRO) Stock Insights
SPRO price $1.17 +0.03 +2.63%
- Ticker
- SPRO
- Price
- $1.17
- Change
- +0.03 +2.63%
- Market cap ?
- $68.13M
- P/E ?
- 7.64
- Forward P/E ?
- 1.56
- Dividend yield ?
- 0.00%
- Beta ?
- 1.50
- Sector
- Healthcare
- Industry
- Biotechnology
- Stocklytics score
- 62
- Value
- 94
- Quality
- 86
- Growth
- 7
Stocklytics score rationale: value 94, quality 86, growth 7.
Financials
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 335000 | 1979000 | 3966000 | 18147000 | 9330000 | 3070000 | 48579000 | 103781000 | 47977000 | 59619000 |
Spero Therapeutics, Inc. is a biopharmaceutical firm in the clinical development stage, primarily focused on discovering, advancing, and commercializing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases within the United States. The company's pipeline includes several key therapeutic candidates: tebipenem pivoxil hydrobromide (HBr), an oral carbapenem-class antibiotic…
Fair value
SPRO fair value $29.32. Price $1.17. Price is 96% below fair value.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
Model uncertainty high for this stock
Earnings
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-11-12 | — | -0.14 | — | — |
| 2026-08-12 | -0.16 | -0.17 | — | — |
| 2026-05-13 | -0.13 | -0.18 | 258.00K | 258.00K |
| 2026-03-26 | 0.53 | -0.20 | 41.30M | 26.00M |
| 2025-11-13 | -0.13 | -0.25 | 3.05M | 12.00M |
| 2025-08-12 | -0.03 | -0.38 | 11.80M | 11.00M |
| 2025-05-13 | -0.25 | -0.55 | 5.87M | 11.00M |
| 2025-03-27 | -0.38 | -0.35 | 9.36M | 6.20M |
| 2024-11-14 | -0.32 | -0.27 | 13.47M | 4.13M |
| 2024-08-05 | -0.33 | -0.35 | 6.02M | 4.90M |
| 2024-05-15 | -0.24 | -0.07 | 4.20M | 21.53M |
| 2024-03-13 | 0.96 | -0.10 | 71.83M | 18.63M |
| 2023-11-13 | 0.02 | -0.15 | 25.47M | 26.63M |
| 2023-08-10 | -0.23 | -0.29 | 788.00K | 11.03M |
| 2023-05-11 | -0.25 | -0.35 | 740.00K | 1.00M |
| 2023-03-30 | 0.55 | 0.04 | 46.30M | 22.87M |
| 2022-11-14 | -0.33 | -0.34 | 1.08M | 5.42M |
| 2022-08-10 | -0.87 | -0.88 | 896.00K | 1.43M |
| 2022-05-16 | -1.01 | -0.87 | 247.00K | 1.93M |
| 2022-03-31 | -0.90 | -0.80 | 2.74M | 4.95M |
| 2021-11-10 | -0.70 | -0.70 | 3.06M | 3.06M |
| 2021-08-05 | -0.63 | -0.77 | 5.15M | 5.15M |
| 2021-05-06 | -0.66 | -0.61 | 7.30M | 3.67M |
| 2021-03-11 | -0.68 | -0.77 | 1.91M | — |
| 2020-11-05 | -0.86 | -0.91 | 4.00M | 573.59K |
| 2020-08-06 | -0.85 | -1.17 | 1.73M | 2.28M |
| 2020-05-08 | -1.22 | -1.35 | 169.00K | 1.74M |
| 2020-03-16 | -1.32 | -1.09 | 696.00K | 2.97M |
| 2019-11-04 | -0.95 | -0.80 | 172.00K | 4.15M |
| 2019-08-08 | -0.74 | -0.57 | 2.16M | 1.89M |
| 2019-05-09 | -0.29 | -0.77 | 3.81M | 20.76M |
| 2019-03-14 | -0.60 | -0.76 | 1.69M | 2.12M |
| 2018-11-08 | -0.60 | -0.64 | 658.00K | 690.90K |
| 2018-08-09 | -0.69 | -0.88 | 463.00K | 516.68K |
| 2018-05-10 | -0.74 | -1.31 | 1.15M | 1.87M |
| 2018-04-02 | -1.59 | -1.56 | 993.00K | 978.96K |
| 2017-12-14 | -36.02 | -2.43 | 597.00K | — |
| 2017-06-30 | -1.39 | — | 249.00K | — |
| 2017-03-31 | -0.89 | — | 140.00K | — |
| 2016-12-31 | -1.09 | — | 335.00K | — |
Dividends
Yield 0.00%. Payout ratio 0.00%. Frequency Quarterly.
Safety score 55/100 · Moderate. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. Dividends were paid in 6 separate years. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| 2015-09-16 | $0.01 | 2015-09-18 | 2015-10-07 | Quarterly |
| 2015-06-17 | $0.01 | 2015-06-19 | 2015-07-07 | Quarterly |
| 2015-03-18 | $0.01 | 2015-03-20 | 2015-04-07 | Quarterly |
| 2014-12-17 | $0.01 | 2014-12-19 | 2015-01-06 | Quarterly |
| 2014-09-17 | $0.01 | 2014-09-19 | 2014-10-07 | Quarterly |
| 2014-06-18 | $0.01 | 2014-06-20 | 2014-07-07 | Quarterly |
| 2014-03-19 | $0.01 | 2014-03-21 | 2014-04-07 | Quarterly |
| 2013-12-17 | $0.01 | 2013-12-19 | 2014-01-06 | Quarterly |
| 2013-09-17 | $0.01 | 2013-09-19 | 2013-10-07 | Quarterly |
| 2013-06-12 | $0.01 | 2013-06-14 | 2013-07-05 | Quarterly |
| 2013-03-20 | $0.01 | 2013-03-22 | 2013-04-05 | Quarterly |
| 2012-12-17 | $0.01 | — | 2013-01-07 | Quarterly |
| 2012-09-17 | $0.01 | — | 2012-10-05 | Quarterly |
| 2012-06-13 | $0.01 | — | 2012-07-06 | Quarterly |
| 2012-03-20 | $0.01 | — | 2012-04-04 | Quarterly |
| 2011-12-12 | $0.01 | — | 2012-01-05 | Quarterly |
| 2011-09-14 | $0.01 | — | 2011-10-05 | Quarterly |
| 2011-06-13 | $0.01 | — | 2011-07-08 | Quarterly |
| 2011-03-22 | $0.01 | — | 2011-04-04 | Quarterly |
| 2010-12-13 | $0.01 | — | 2010-12-31 | Quarterly |
| 2010-09-29 | $0.01 | — | 2010-10-11 | Quarterly |
| 2010-06-29 | $0.01 | — | 2010-07-12 | Quarterly |
| 2010-03-30 | $0.01 | — | 2010-04-11 | Quarterly |
Insider trades
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-08-03 | Zack Debra | Buy | 324.68K | $1.54 | 500.00K |
| 2026-08-03 | Zack Debra | Buy | 162.31K | — | — |
| 2026-08-03 | Zack Debra | Other | 0 | — | — |
| 2026-06-23 | Deshpande Milind | Buy | 10.00K | — | — |
| 2026-06-23 | Deshpande Milind | Buy | 20.00K | $2.15 | 43.00K |
| 2026-06-23 | Tregoning Kathleen | Buy | 10.00K | — | — |
| 2026-06-23 | Tregoning Kathleen | Buy | 20.00K | $2.15 | 43.00K |
| 2026-06-23 | Smith Cynthia | Buy | 10.00K | — | — |
| 2026-06-23 | Smith Cynthia | Buy | 20.00K | $2.15 | 43.00K |
| 2026-06-23 | VINK PATRICK V.J.J. | Buy | 10.00K | — | — |
| 2026-06-23 | VINK PATRICK V.J.J. | Buy | 20.00K | $2.15 | 43.00K |
| 2026-06-23 | THOMAS FRANK E | Buy | 10.00K | — | — |
| 2026-06-23 | THOMAS FRANK E | Buy | 20.00K | $2.15 | 43.00K |
| 2026-06-23 | Jackson Scott Thomas | Buy | 10.00K | — | — |
| 2026-06-23 | Jackson Scott Thomas | Buy | 20.00K | $2.15 | 43.00K |
| 2026-06-23 | Pottage John C Jr | Buy | 10.00K | — | — |
| 2026-06-23 | Pottage John C Jr | Buy | 20.00K | $2.15 | 43.00K |
| 2026-05-04 | Rajavelu Esther | Sell | 25.24K | $2.51 | 63.35K |
| 2026-02-06 | Rajavelu Esther | Sell | 37.10K | $2.36 | 87.56K |
| 2026-02-06 | Rajavelu Esther | Sell | 50.82K | $2.36 | 119.93K |
| 2026-02-06 | Keutzer Timothy | Sell | 18.65K | $2.36 | 44.02K |
| 2026-02-04 | Keutzer Timothy | Sell | 3.47K | $2.24 | 7.78K |
| 2026-02-03 | Keutzer Timothy | Sell | 24.22K | $2.14 | 51.84K |
| 2026-02-02 | Keutzer Timothy | Buy | 68.00K | — | — |
| 2026-02-02 | Keutzer Timothy | Sell | 18.89K | $2.20 | 41.56K |
| 2026-02-02 | Keutzer Timothy | Buy | 137.00K | $2.23 | 305.51K |
| 2026-02-02 | Rajavelu Esther | Buy | 249.00K | — | — |
| 2026-02-02 | Rajavelu Esther | Sell | 18.44K | $2.20 | 40.57K |
| 2026-02-02 | Rajavelu Esther | Buy | 498.00K | $2.23 | 1.11M |
| 2025-11-07 | Rajavelu Esther | Sell | 40.27K | $2.37 | 95.44K |
| 2025-08-28 | Mahadevia Ankit | Sell | 6.57K | $1.97 | 12.95K |
| 2025-08-28 | Keutzer Timothy | Sell | 1.70K | $1.97 | 3.34K |
| 2025-06-12 | Mahadevia Ankit | Buy | 20.00K | — | — |
| 2025-06-12 | Deshpande Milind | Buy | 20.00K | — | — |
| 2025-06-12 | Jackson Scott Thomas | Buy | 20.00K | — | — |
| 2025-06-12 | VINK PATRICK V.J.J. | Buy | 20.00K | — | — |
| 2025-06-12 | Pottage John C Jr | Buy | 20.00K | — | — |
| 2025-06-12 | Smith Cynthia | Buy | 20.00K | — | — |
| 2025-06-12 | THOMAS FRANK E | Buy | 20.00K | — | — |
| 2025-06-12 | Tregoning Kathleen | Buy | 20.00K | — | — |
| 2025-05-02 | Rajavelu Esther | Buy | 185.00K | — | — |
| 2025-02-05 | Keutzer Timothy | Sell | 3.97K | $0.78 | 3.10K |
| 2025-02-05 | Keutzer Timothy | Sell | 27.64K | $0.78 | 21.56K |
| 2025-02-05 | Keutzer Timothy | Sell | 24.92K | $0.78 | 19.44K |
| 2025-02-05 | Rajavelu Esther | Sell | 20.69K | $0.78 | 16.14K |
| 2025-02-05 | Shukla Sath | Sell | 6.14K | $0.78 | 4.79K |
| 2025-02-05 | Shukla Sath | Sell | 42.79K | $0.78 | 33.37K |
| 2025-02-05 | Shukla Sath | Sell | 106.41K | $0.78 | 83.00K |
| 2025-02-05 | Mahadevia Ankit | Sell | 13.96K | $0.78 | 10.89K |
| 2025-02-05 | Mahadevia Ankit | Sell | 55.26K | $0.78 | 43.10K |
| 2025-02-03 | Keutzer Timothy | Buy | 266.14K | — | — |
| 2025-02-03 | Rajavelu Esther | Buy | 100.00K | — | — |
| 2025-02-03 | Rajavelu Esther | Buy | 266.14K | — | — |
| 2025-02-03 | Shukla Sath | Buy | 751.41K | — | — |
| 2024-11-08 | Rajavelu Esther | Sell | 17.25K | $1.30 | 22.42K |
| 2024-11-07 | Rajavelu Esther | Sell | 23.35K | $1.31 | 30.59K |
| 2024-08-27 | Mahadevia Ankit | Sell | 5.91K | $1.35 | 7.98K |
| 2024-08-27 | Keutzer Timothy | Sell | 2.21K | $1.35 | 2.99K |
| 2024-08-27 | Shukla Sath | Sell | 2.76K | $1.35 | 3.72K |
| 2024-08-05 | Shukla Sath | Sell | 17.64K | $1.31 | 23.11K |
| 2024-08-02 | Shukla Sath | Sell | 14.80K | $1.32 | 19.54K |
| 2024-05-29 | Deshpande Milind | Buy | 20.00K | — | — |
| 2024-05-29 | Jackson Scott Thomas | Buy | 20.00K | — | — |
| 2024-05-29 | Mahadevia Ankit | Buy | 20.00K | — | — |
| 2024-05-29 | VINK PATRICK V.J.J. | Buy | 20.00K | — | — |
| 2024-05-29 | Tregoning Kathleen | Buy | 20.00K | — | — |
| 2024-05-29 | Smith Cynthia | Buy | 20.00K | — | — |
| 2024-05-29 | THOMAS FRANK E | Buy | 20.00K | — | — |
| 2024-05-29 | Pottage John C Jr | Buy | 20.00K | — | — |
| 2024-02-05 | Shukla Sath | Sell | 45.09K | $1.45 | 65.38K |
| 2024-02-02 | Keutzer Timothy | Sell | 30.97K | $1.36 | 42.12K |
| 2024-02-02 | Mahadevia Ankit | Sell | 63.80K | $1.37 | 87.40K |
| 2024-02-02 | JOSEPH TAMARA L | Sell | 30.91K | $1.37 | 42.34K |
| 2024-02-02 | HAMED KAMAL | Sell | 28.07K | $1.37 | 38.46K |
| 2024-02-02 | Shukla Sath | Sell | 30.90K | $1.37 | 42.33K |
| 2024-02-01 | Keutzer Timothy | Buy | 239.73K | — | — |
| 2024-02-01 | JOSEPH TAMARA L | Buy | 239.73K | — | — |
| 2024-02-01 | HAMED KAMAL | Buy | 239.73K | — | — |
| 2024-02-01 | Rajavelu Esther | Buy | 119.87K | — | — |
| 2024-02-01 | Shukla Sath | Buy | 679.50K | — | — |
| 2024-01-02 | Tregoning Kathleen | Buy | 35.60K | $1.52 | 54.12K |
| 2023-11-13 | Rajavelu Esther | Buy | 300.00K | — | — |
| 2023-11-06 | Rajavelu Esther | Other | 0 | — | — |
| 2023-10-05 | Pottage John C Jr | Buy | 20.00K | — | — |
| 2023-10-05 | Smith Cynthia | Buy | 20.00K | — | — |
| 2023-10-05 | THOMAS FRANK E | Buy | 20.00K | — | — |
| 2023-10-05 | Deshpande Milind | Buy | 20.00K | — | — |
| 2023-10-05 | Tregoning Kathleen | Buy | 20.00K | — | — |
| 2023-10-05 | VINK PATRICK V.J.J. | Buy | 20.00K | — | — |
| 2023-10-05 | Jackson Scott Thomas | Buy | 20.00K | — | — |
| 2023-10-05 | Mahadevia Ankit | Buy | 20.00K | — | — |
| 2023-09-13 | HAMED KAMAL | Sell | 39.50K | $1.27 | 50.16K |
| 2023-08-29 | Shukla Sath | Sell | 4.16K | $1.30 | 5.41K |
| 2023-08-28 | Keutzer Timothy | Sell | 1.85K | $1.26 | 2.34K |
| 2023-08-28 | JOSEPH TAMARA L | Sell | 1.85K | $1.26 | 2.34K |
| 2023-08-28 | Mahadevia Ankit | Sell | 9.04K | $1.26 | 11.39K |
| 2023-08-28 | Shukla Sath | Sell | 1.85K | $1.26 | 2.34K |
| 2023-08-01 | Shukla Sath | Buy | 266.00K | — | — |
| 2023-07-15 | DiPalma Stephen J. | Other | 0 | — | — |
| 2023-06-12 | HAMED KAMAL | Buy | 140.00K | — | — |
Institutional holders
Latest filed quarter: Q2 2026.
Institutions holding: 66, holders +11 vs prior quarter. Ownership 37.06%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| GSK PLC | 9.19M | 0 | 0.00% | 20.31M |
| PFIZER INC | 2.36M | 0 | 0.00% | 5.34M |
| VANGUARD CAPITAL MANAGEMENT LLC | 2.04M | 236.35K | +13.13% | 4.50M |
| RENAISSANCE TECHNOLOGIES LLC | 947.90K | -241.33K | -20.29% | 2.09M |
| ALPHABET INC. | 889.98K | 0 | 0.00% | 1.97M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 759.29K | 710.79K | +1465.55% | 1.68M |
| BLACKROCK, INC. | 594.40K | 161.20K | +37.21% | 1.31M |
| GEODE CAPITAL MANAGEMENT, LLC | 566.33K | 46.41K | +8.93% | 1.25M |
| RAYMOND JAMES FINANCIAL INC | 521.71K | 521.71K | New | 1.15M |
| TWO SIGMA INVESTMENTS, LP | 382.81K | -502.82K | -56.77% | 846.02K |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 332.97K | 332.97K | New | 735.86K |
| VANGUARD FIDUCIARY TRUST CO | 287.65K | 23.53K | +8.91% | 635.70K |
| GSA CAPITAL PARTNERS LLP | 285.91K | 7.60K | +2.73% | 632.00K |
| DIMENSIONAL FUND ADVISORS LP | 274.82K | 245.05K | +823.21% | 607.62K |
| GOLDMAN SACHS GROUP INC | 256.99K | 256.99K | New | 567.94K |
| STATE STREET CORP | 214.75K | 0 | 0.00% | 474.60K |
| JANE STREET GROUP, LLC | 158.10K | 120.30K | +318.25% | 349.39K |
| UBS GROUP AG | 139.68K | 136.67K | +4542.07% | 308.69K |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 114.80K | 0 | 0.00% | 253.71K |
| NORTHERN TRUST CORP | 108.27K | -12.71K | -10.51% | 239.29K |
| POINT72 ASSET MANAGEMENT, L.P. | 104.38K | 44.71K | +74.93% | 230.67K |
| IONIC CAPITAL MANAGEMENT LLC | 102.70K | -93.24K | -47.59% | 226.96K |
| FEDERATION DES CAISSES DESJARDINS DU QUEBEC | 91.90K | 91.90K | New | 202.18K |
| SHAY CAPITAL LLC | 72.39K | 2.04K | +2.90% | 159.98K |
| CITADEL ADVISORS LLC | 65.60K | 43.10K | +191.56% | 144.98K |
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