Alnylam Pharmaceuticals (ALNY) Fair Value & DCF
ALNY price $161.08 —
- Ticker
- ALNY
- Price
- $161.08
- Change
- —
- Market cap ?
- $20.23B
- P/E ?
- 7.70
- Forward P/E ?
- 22.26
- Dividend yield ?
- 0.00%
- Beta ?
- 0.27
- Sector
- Healthcare
- Industry
- Biotechnology
- Stocklytics score
- 79
- Value
- 63
- Quality
- 75
- Growth
- 100
Stocklytics score rationale: value 63, quality 75, growth 100.
AI Score 85. Alnylam Pharmaceuticals has a strong market capitalization of approximately $21.57 billion and impressive profitability metrics, including a net profit margin of 54.3%. The company also shows robust growth potential with a price-to-earnings ratio of about 7.9 and a solid pipeline of RNAi-based therapies, indicating strong future revenue prospects
Summary
Alnylam Pharmaceuticals, Inc. operates in the Healthcare sector and Biotechnology industry. The company reports a P/E ratio of 8.1 and a net margin of 54.3%.
Valuation
The P/E ratio of 8.1 is low relative to the company’s reported profitability, while price-to-book is 6.1. The available facts do not provide revenue, earnings estimates, or price-trend data for a fuller valuation assessment.
Quality
A net margin of 54.3% indicates strong reported profitability. However, the provided facts do not include balance-sheet, cash-flow, or return-on-capital measures.
Growth
No revenue, earnings-growth, guidance, or analyst-estimate information is provided. Growth cannot be assessed from the available facts.
Risks
The shares trade at 6.1 times book value, which may leave valuation sensitive to changes in expectations. There is no dividend yield, and the available facts provide limited visibility into growth and financial durability.
Fair value
ALNY fair value $285.22. Price $161.08. Price is 44% below fair value.
Below fair value, and cheaper than usual. A larger discount than on 87% of days in the past 5 years.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price.
Fair value blends a 10-year DCF and an earnings multiple: the average of the DCF value and an earnings value from next-twelve-months EPS times 29.2, a blend of the industry median and the stock's own 10-year median. How we calculate it →
Compare ALNY
Earnings
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|
| 2027-02-11 | — | 1.72 | — | 1.53B |
| 2026-10-29 | 16.26 | 1.66 | 1.46B | 1.43B |
| 2026-07-30 | 1.21 | 1.63 | 1.29B | 1.32B |
| 2026-04-30 | 1.51 | 0.87 | 1.17B | 1.12B |
| 2026-02-12 | 0.82 | 1.16 | 1.10B | 1.15B |
| 2025-10-30 | 1.84 | 0.56 | 1.25B | 959.40M |
| 2025-07-31 | -0.51 | -0.54 | 773.69M | 662.87M |
| 2025-05-01 | -0.44 | -0.89 | 594.19M | 585.14M |
| 2025-02-13 | -0.65 | -0.62 | 593.17M | 582.61M |
| 2024-10-31 | -0.87 | -0.92 | 500.92M | 532.91M |
| 2024-08-01 | -0.13 | -1.07 | 659.83M | 447.22M |
| 2024-05-02 | -0.52 | -1.12 | 494.33M | 428.01M |
| 2024-02-15 | -1.10 | -1.20 | 439.72M | 436.92M |
| 2023-11-02 | 1.15 | -1.34 | 750.53M | 396.76M |
| 2023-08-03 | -2.21 | -1.37 | 318.75M | 332.28M |
| 2023-05-04 | -1.40 | -1.77 | 319.29M | 312.27M |
| 2023-02-23 | -1.68 | -1.90 | 335.04M | 313.13M |
| 2022-10-27 | -3.32 | -1.77 | 264.31M | 291.66M |
| 2022-07-28 | -2.29 | -1.63 | 224.82M | 255.56M |
| 2022-04-28 | -2.00 | -1.84 | 213.26M | 240.95M |
| 2022-02-10 | -2.16 | -1.54 | 258.54M | 233.61M |
| 2021-10-28 | -1.72 | -1.57 | 187.63M | 219.69M |
| 2021-08-03 | -1.61 | -1.61 | 220.55M | 220.55M |
| 2021-04-29 | -1.71 | -1.73 | 177.57M | 169.04M |
| 2021-02-11 | -2.09 | -1.78 | 163.56M | 146.70M |
| 2020-11-05 | -2.18 | -1.64 | 125.85M | 95.83M |
| 2020-08-06 | -1.56 | -1.71 | 103.96M | 115.96M |
| 2020-05-06 | -1.62 | -1.88 | 99.48M | 116.06M |
| 2020-02-06 | -2.47 | -2.21 | 71.68M | 64.43M |
| 2019-10-31 | -1.92 | -2.04 | 70.06M | 74.44M |
| 2019-08-06 | -2.02 | -1.85 | 44.71M | 41.17M |
| 2019-05-01 | -1.73 | -2.07 | 33.29M | 39.84M |
| 2019-02-07 | -2.09 | -2.21 | 21.03M | 22.24M |
| 2018-11-07 | -2.43 | -1.73 | 2.07M | 1.70M |
| 2018-08-02 | -1.61 | -1.75 | 29.91M | 32.11M |
| 2018-05-03 | -1.41 | -1.47 | 21.90M | 22.83M |
| 2018-02-08 | -1.48 | -1.39 | 37.92M | 35.61M |
| 2017-11-07 | -1.34 | -1.26 | 17.10M | 16.08M |
| 2017-08-09 | -1.34 | -1.22 | 15.93M | 14.50M |
| 2017-05-05 | -1.25 | -1.26 | 18.96M | 19.11M |
Dividends
Yield 0.00%. Payout ratio 0.00%. Frequency —.
Safety score 37/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. No dividend history was found. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|
| No data yet. |
Insider trades
| Date | Insider | Action | Shares | Price | Value |
|---|
| 2026-10-02 | SUPRAN BRYAN | Sell | 1.76K | $226.88 | 398.86K |
| 2026-09-19 | Greenstreet Yvonne | Buy | 107 | — | — |
| 2026-06-01 | PYOTT DAVID E I | Buy | 3.83K | — | — |
| 2026-06-01 | PYOTT DAVID E I | Sell | 921 | $297.71 | 274.19K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 1.18K | $298.91 | 351.22K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 1.22K | $299.87 | 366.44K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 495 | $300.72 | 148.86K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 17 | $302.65 | 5.15K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 3.83K | $70.20 | 268.87K |
| 2026-06-01 | Cravatt Benjamin | Buy | 4.39K | $295.63 | 1.30M |
| 2026-06-01 | Cravatt Benjamin | Other | 0 | — | — |
| 2026-05-20 | Sigal Charles Elliott | Buy | 671 | — | — |
| 2026-05-20 | Sigal Charles Elliott | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | SCHULMAN AMY W | Buy | 838 | — | — |
| 2026-05-20 | SCHULMAN AMY W | Buy | 1.80K | $298.48 | 537.86K |
| 2026-05-20 | Reitan Colleen F | Buy | 671 | — | — |
| 2026-05-20 | Reitan Colleen F | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | PYOTT DAVID E I | Buy | 671 | — | — |
| 2026-05-20 | PYOTT DAVID E I | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | KELLOGG PETER N | Buy | 671 | — | — |
| 2026-05-20 | KELLOGG PETER N | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | HAMBURG MARGARET A | Buy | 671 | — | — |
| 2026-05-20 | HAMBURG MARGARET A | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | BRANDICOURT OLIVIER | Buy | 671 | — | — |
| 2026-05-20 | BRANDICOURT OLIVIER | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | Ausiello Dennis A | Buy | 671 | — | — |
| 2026-05-20 | Ausiello Dennis A | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | Arbuckle Stuart A | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | Arbuckle Stuart A | Buy | 671 | — | — |
| 2026-05-13 | SCHULMAN AMY W | Buy | 11.25K | $70.20 | 789.75K |
| 2026-05-13 | SCHULMAN AMY W | Sell | 11.25K | $70.20 | 789.75K |
| 2026-04-06 | McLaughlin Melissa | Sell | 56 | $320.14 | 17.93K |
| 2026-04-06 | McLaughlin Melissa | Sell | 909 | $329.76 | 299.75K |
| 2026-04-06 | McLaughlin Melissa | Sell | 829 | $330.46 | 273.95K |
| 2026-04-06 | McLaughlin Melissa | Sell | 293 | $331.89 | 97.24K |
| 2026-04-06 | McLaughlin Melissa | Sell | 199 | $333.94 | 66.45K |
| 2026-04-02 | McLaughlin Melissa | Sell | 265 | $316.61 | 83.90K |
| 2026-04-02 | McLaughlin Melissa | Sell | 359 | $317.44 | 113.96K |
| 2026-04-02 | McLaughlin Melissa | Sell | 209 | $318.47 | 66.56K |
| 2026-04-02 | McLaughlin Melissa | Sell | 86 | $319.69 | 27.49K |
| 2026-04-02 | McLaughlin Melissa | Sell | 147 | $320.62 | 47.13K |
| 2026-04-02 | McLaughlin Melissa | Sell | 224 | $321.64 | 72.05K |
| 2026-04-02 | McLaughlin Melissa | Sell | 245 | $322.86 | 79.10K |
| 2026-04-02 | McLaughlin Melissa | Sell | 81 | $323.64 | 26.21K |
| 2026-04-02 | McLaughlin Melissa | Sell | 8 | $325.49 | 2.60K |
| 2026-03-25 | McLaughlin Melissa | Other | 0 | — | — |
| 2026-03-25 | McLaughlin Melissa | Other | 3.57K | $325.07 | 1.16M |
| 2026-03-05 | Garg Pushkal | Sell | 654 | $322.33 | 210.80K |
| 2026-03-05 | Garg Pushkal | Sell | 740 | $323.55 | 239.43K |
| 2026-03-05 | Garg Pushkal | Sell | 510 | $324.59 | 165.54K |
| 2026-03-05 | Garg Pushkal | Sell | 500 | $326.08 | 163.04K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 124 | $321.81 | 39.90K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 233 | $323.25 | 75.32K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 148 | $324.60 | 48.04K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 153 | $326.24 | 49.91K |
| 2026-03-04 | Garg Pushkal | Sell | 106 | $319.03 | 33.82K |
| 2026-03-04 | Garg Pushkal | Sell | 102 | $320.01 | 32.64K |
| 2026-03-04 | Garg Pushkal | Sell | 215 | $320.81 | 68.97K |
| 2026-03-04 | Garg Pushkal | Sell | 289 | $321.82 | 93.01K |
| 2026-03-04 | Garg Pushkal | Sell | 350 | $323.01 | 113.05K |
| 2026-03-04 | Garg Pushkal | Sell | 767 | $323.84 | 248.39K |
| 2026-03-04 | Garg Pushkal | Sell | 272 | $324.88 | 88.37K |
| 2026-03-04 | Garg Pushkal | Sell | 208 | $325.67 | 67.74K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 135 | $319.03 | 43.07K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 129 | $320.01 | 41.28K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 274 | $320.81 | 87.90K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 368 | $321.82 | 118.43K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 444 | $323.01 | 143.42K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 973 | $323.84 | 315.10K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 345 | $324.88 | 112.08K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 265 | $325.67 | 86.30K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 114 | $319.03 | 36.37K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 109 | $320.01 | 34.88K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 230 | $320.81 | 73.79K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 309 | $321.82 | 99.44K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 374 | $323.01 | 120.81K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 818 | $323.84 | 264.90K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 291 | $324.88 | 94.54K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 223 | $325.67 | 72.62K |
| 2026-03-04 | Tanguler Tolga | Sell | 106 | $319.03 | 33.82K |
| 2026-03-04 | Tanguler Tolga | Sell | 102 | $320.01 | 32.64K |
| 2026-03-04 | Tanguler Tolga | Sell | 215 | $320.81 | 68.97K |
| 2026-03-04 | Tanguler Tolga | Sell | 289 | $321.82 | 93.01K |
| 2026-03-04 | Tanguler Tolga | Sell | 350 | $323.01 | 113.05K |
| 2026-03-04 | Tanguler Tolga | Sell | 767 | $323.84 | 248.39K |
| 2026-03-04 | Tanguler Tolga | Sell | 272 | $324.88 | 88.37K |
| 2026-03-04 | Tanguler Tolga | Sell | 208 | $325.67 | 67.74K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 29 | $319.03 | 9.25K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 28 | $320.01 | 8.96K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 59 | $320.81 | 18.93K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 79 | $321.82 | 25.42K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 96 | $323.01 | 31.01K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 210 | $323.84 | 68.01K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 75 | $324.88 | 24.37K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 57 | $325.67 | 18.56K |
| 2026-03-02 | Poulton Jeffrey V. | Buy | 4.77K | — | — |
| 2026-03-02 | Poulton Jeffrey V. | Sell | 65 | $323.62 | 21.04K |
| 2026-03-02 | Poulton Jeffrey V. | Sell | 124 | $324.65 | 40.26K |
| 2026-03-02 | Poulton Jeffrey V. | Sell | 356 | $325.63 | 115.92K |
| 2026-03-02 | Poulton Jeffrey V. | Sell | 541 | $326.81 | 176.80K |
Institutional holders
Latest filed quarter: Q2 2026.
Institutions holding: 830, holders +2 vs prior quarter. Ownership 100.97%.
| Holder | Shares | Change | Change % | Value |
|---|
| FMR LLC | 15.02M | 444.80K | +3.05% | 4.52B |
| CAPITAL WORLD INVESTORS | 11.14M | 342.50K | +3.17% | 3.35B |
| BLACKROCK, INC. | 10.91M | 462.77K | +4.43% | 3.28B |
| CAPITAL RESEARCH GLOBAL INVESTORS | 9.75M | 279.52K | +2.95% | 2.94B |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 6.54M | 47.11K | +0.73% | 1.97B |
| VANGUARD CAPITAL MANAGEMENT LLC | 6.03M | 82.77K | +1.39% | 1.82B |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 5.64M | 448.85K | +8.64% | 1.70B |
| INVESCO LTD. | 3.75M | 970.92K | +34.88% | 1.13B |
| STATE STREET CORP | 3.56M | 232.99K | +7.01% | 1.07B |
| GEODE CAPITAL MANAGEMENT, LLC | 2.64M | -24.55K | -0.92% | 791.35M |
| JPMORGAN CHASE & CO | 2.68M | -3.65M | -57.69% | 785.32M |
| BAILLIE GIFFORD & CO | 2.44M | -53.98K | -2.16% | 734.48M |
| NORGES BANK | 2.27M | 2.27M | New | 683.88M |
| WELLINGTON MANAGEMENT GROUP LLP | 2.11M | 174.48K | +9.01% | 635.30M |
| ORBIS ALLAN GRAY LTD | 1.99M | 652.58K | +48.89% | 598.27M |
| DODGE & COX | 1.96M | 26.14K | +1.35% | 588.63M |
| TWO SIGMA INVESTMENTS, LP | 1.88M | -116.64K | -5.85% | 564.71M |
| AMERICAN CENTURY COMPANIES INC | 1.85M | 51.59K | +2.86% | 558.10M |
| CLEARBRIDGE INVESTMENTS, LLC | 1.26M | -96.55K | -7.12% | 379.14M |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.15M | -283.55K | -19.79% | 345.94M |
| D. E. SHAW & CO., INC. | 1.10M | 695.31K | +170.09% | 332.37M |
| MORGAN STANLEY | 1.03M | 29.47K | +2.94% | 310.71M |
| BANK OF AMERICA CORP /DE/ | 994.48K | 27.56K | +2.85% | 299.37M |
| LEGAL & GENERAL GROUP PLC | 924.56K | -10.32K | -1.10% | 278.32M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 893.79K | 231.43K | +34.94% | 269.06M |
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