Alnylam Pharmaceuticals (ALNY) Stock Insights
$30.66B
Market Cap
37.32
P/E
35.31
Forward P/E
70
Score
ALNY price $229.16 +2.37 +1.05%
Stocklytics score rationale: value 51, quality 80, growth 80.
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 47159000 | 89912000 | 74908000 | 219750000 | 492853000 | 844287000 | 1037418000 | 1828292000 | 2248243000 | 3713937000 |
Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company primarily dedicated to the discovery, development, and commercialization of innovative therapeutic solutions leveraging ribonucleic acid interference (RNAi) technology. Its robust pipeline of RNAi-based treatments addresses a range of critical therapeutic areas, including inherited genetic disorders, cardio-metabolic conditions, hepatic infectious…
ALNY fair value $371.50. Price $229.16. Price is 38% below fair value.
Below fair value, and cheaper than usual. A larger discount than on 95% of days in the past 5 years.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-10-29 | — | 1.66 | — | 1.43B |
| 2026-07-30 | 1.21 | 1.63 | 1.29B | 1.32B |
| 2026-04-30 | 1.51 | 0.87 | 1.17B | 1.12B |
| 2026-02-12 | 0.82 | 1.16 | 1.10B | 1.15B |
| 2025-10-30 | 1.84 | 0.56 | 1.25B | 959.40M |
| 2025-07-31 | -0.51 | -0.54 | 773.69M | 662.87M |
| 2025-05-01 | -0.44 | -0.89 | 594.19M | 585.14M |
| 2025-02-13 | -0.65 | -0.62 | 593.17M | 582.61M |
| 2024-10-31 | -0.87 | -0.92 | 500.92M | 532.91M |
| 2024-08-01 | -0.13 | -1.07 | 659.83M | 447.22M |
| 2024-05-02 | -0.52 | -1.12 | 494.33M | 428.01M |
| 2024-02-15 | -1.10 | -1.20 | 439.72M | 436.92M |
| 2023-11-02 | 1.15 | -1.34 | 750.53M | 396.76M |
| 2023-08-03 | -2.21 | -1.37 | 318.75M | 332.28M |
| 2023-05-04 | -1.40 | -1.77 | 319.29M | 312.27M |
| 2023-02-23 | -1.68 | -1.90 | 335.04M | 313.13M |
| 2022-10-27 | -3.32 | -1.77 | 264.31M | 291.66M |
| 2022-07-28 | -2.29 | -1.63 | 224.82M | 255.56M |
| 2022-04-28 | -2.00 | -1.84 | 213.26M | 240.95M |
| 2022-02-10 | -2.16 | -1.54 | 258.54M | 233.61M |
| 2021-10-28 | -1.72 | -1.57 | 187.63M | 219.69M |
| 2021-08-03 | -1.61 | -1.61 | 220.55M | 220.55M |
| 2021-04-29 | -1.71 | -1.73 | 177.57M | 169.04M |
| 2021-02-11 | -2.09 | -1.78 | 163.56M | 146.70M |
| 2020-11-05 | -2.18 | -1.64 | 125.85M | 95.83M |
| 2020-08-06 | -1.56 | -1.71 | 103.96M | 115.96M |
| 2020-05-06 | -1.62 | -1.88 | 99.48M | 116.06M |
| 2020-02-06 | -2.47 | -2.21 | 71.68M | 64.43M |
| 2019-10-31 | -1.92 | -2.04 | 70.06M | 74.44M |
| 2019-08-06 | -2.02 | -1.85 | 44.71M | 41.17M |
| 2019-05-01 | -1.73 | -2.07 | 33.29M | 39.84M |
| 2019-02-07 | -2.09 | -2.21 | 21.03M | 22.24M |
| 2018-11-07 | -2.43 | -1.73 | 2.07M | 1.70M |
| 2018-08-02 | -1.61 | -1.75 | 29.91M | 32.11M |
| 2018-05-03 | -1.41 | -1.47 | 21.90M | 22.83M |
| 2018-02-08 | -1.48 | -1.39 | 37.92M | 35.61M |
| 2017-11-07 | -1.34 | -1.26 | 17.10M | 16.08M |
| 2017-08-09 | -1.34 | -1.22 | 15.93M | 14.50M |
| 2017-05-05 | -1.25 | -1.26 | 18.96M | 19.11M |
| 2017-02-08 | -1.32 | -1.33 | 17.45M | 17.58M |
Yield 0.00%. Payout ratio 0.00%. Frequency —.
Safety score 37/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. No dividend history was found. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| No data yet. | ||||
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-10-02 | SUPRAN BRYAN | Sell | 1.76K | $226.88 | 398.86K |
| 2026-09-19 | Greenstreet Yvonne | Buy | 107 | — | — |
| 2026-06-01 | PYOTT DAVID E I | Buy | 3.83K | — | — |
| 2026-06-01 | PYOTT DAVID E I | Sell | 921 | $297.71 | 274.19K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 1.18K | $298.91 | 351.22K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 1.22K | $299.87 | 366.44K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 495 | $300.72 | 148.86K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 17 | $302.65 | 5.15K |
| 2026-06-01 | PYOTT DAVID E I | Sell | 3.83K | $70.20 | 268.87K |
| 2026-06-01 | Cravatt Benjamin | Buy | 4.39K | $295.63 | 1.30M |
| 2026-06-01 | Cravatt Benjamin | Other | 0 | — | — |
| 2026-05-20 | Sigal Charles Elliott | Buy | 671 | — | — |
| 2026-05-20 | Sigal Charles Elliott | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | SCHULMAN AMY W | Buy | 838 | — | — |
| 2026-05-20 | SCHULMAN AMY W | Buy | 1.80K | $298.48 | 537.86K |
| 2026-05-20 | Reitan Colleen F | Buy | 671 | — | — |
| 2026-05-20 | Reitan Colleen F | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | PYOTT DAVID E I | Buy | 671 | — | — |
| 2026-05-20 | PYOTT DAVID E I | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | KELLOGG PETER N | Buy | 671 | — | — |
| 2026-05-20 | KELLOGG PETER N | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | HAMBURG MARGARET A | Buy | 671 | — | — |
| 2026-05-20 | HAMBURG MARGARET A | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | BRANDICOURT OLIVIER | Buy | 671 | — | — |
| 2026-05-20 | BRANDICOURT OLIVIER | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | Ausiello Dennis A | Buy | 671 | — | — |
| 2026-05-20 | Ausiello Dennis A | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | Arbuckle Stuart A | Buy | 1.44K | $298.48 | 430.11K |
| 2026-05-20 | Arbuckle Stuart A | Buy | 671 | — | — |
| 2026-05-13 | SCHULMAN AMY W | Buy | 11.25K | $70.20 | 789.75K |
| 2026-05-13 | SCHULMAN AMY W | Sell | 11.25K | $70.20 | 789.75K |
| 2026-04-06 | McLaughlin Melissa | Sell | 56 | $320.14 | 17.93K |
| 2026-04-06 | McLaughlin Melissa | Sell | 909 | $329.76 | 299.75K |
| 2026-04-06 | McLaughlin Melissa | Sell | 829 | $330.46 | 273.95K |
| 2026-04-06 | McLaughlin Melissa | Sell | 293 | $331.89 | 97.24K |
| 2026-04-06 | McLaughlin Melissa | Sell | 199 | $333.94 | 66.45K |
| 2026-04-02 | McLaughlin Melissa | Sell | 265 | $316.61 | 83.90K |
| 2026-04-02 | McLaughlin Melissa | Sell | 359 | $317.44 | 113.96K |
| 2026-04-02 | McLaughlin Melissa | Sell | 209 | $318.47 | 66.56K |
| 2026-04-02 | McLaughlin Melissa | Sell | 86 | $319.69 | 27.49K |
| 2026-04-02 | McLaughlin Melissa | Sell | 147 | $320.62 | 47.13K |
| 2026-04-02 | McLaughlin Melissa | Sell | 224 | $321.64 | 72.05K |
| 2026-04-02 | McLaughlin Melissa | Sell | 245 | $322.86 | 79.10K |
| 2026-04-02 | McLaughlin Melissa | Sell | 81 | $323.64 | 26.21K |
| 2026-04-02 | McLaughlin Melissa | Sell | 8 | $325.49 | 2.60K |
| 2026-03-25 | McLaughlin Melissa | Other | 0 | — | — |
| 2026-03-25 | McLaughlin Melissa | Other | 3.57K | $325.07 | 1.16M |
| 2026-03-05 | Garg Pushkal | Sell | 654 | $322.33 | 210.80K |
| 2026-03-05 | Garg Pushkal | Sell | 740 | $323.55 | 239.43K |
| 2026-03-05 | Garg Pushkal | Sell | 510 | $324.59 | 165.54K |
| 2026-03-05 | Garg Pushkal | Sell | 500 | $326.08 | 163.04K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 124 | $321.81 | 39.90K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 233 | $323.25 | 75.32K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 148 | $324.60 | 48.04K |
| 2026-03-05 | Fitzgerald Kevin Joseph | Sell | 153 | $326.24 | 49.91K |
| 2026-03-04 | Garg Pushkal | Sell | 106 | $319.03 | 33.82K |
| 2026-03-04 | Garg Pushkal | Sell | 102 | $320.01 | 32.64K |
| 2026-03-04 | Garg Pushkal | Sell | 215 | $320.81 | 68.97K |
| 2026-03-04 | Garg Pushkal | Sell | 289 | $321.82 | 93.01K |
| 2026-03-04 | Garg Pushkal | Sell | 350 | $323.01 | 113.05K |
| 2026-03-04 | Garg Pushkal | Sell | 767 | $323.84 | 248.39K |
| 2026-03-04 | Garg Pushkal | Sell | 272 | $324.88 | 88.37K |
| 2026-03-04 | Garg Pushkal | Sell | 208 | $325.67 | 67.74K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 135 | $319.03 | 43.07K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 129 | $320.01 | 41.28K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 274 | $320.81 | 87.90K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 368 | $321.82 | 118.43K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 444 | $323.01 | 143.42K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 973 | $323.84 | 315.10K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 345 | $324.88 | 112.08K |
| 2026-03-04 | Greenstreet Yvonne | Sell | 265 | $325.67 | 86.30K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 114 | $319.03 | 36.37K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 109 | $320.01 | 34.88K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 230 | $320.81 | 73.79K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 309 | $321.82 | 99.44K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 374 | $323.01 | 120.81K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 818 | $323.84 | 264.90K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 291 | $324.88 | 94.54K |
| 2026-03-04 | Poulton Jeffrey V. | Sell | 223 | $325.67 | 72.62K |
| 2026-03-04 | Tanguler Tolga | Sell | 106 | $319.03 | 33.82K |
| 2026-03-04 | Tanguler Tolga | Sell | 102 | $320.01 | 32.64K |
| 2026-03-04 | Tanguler Tolga | Sell | 215 | $320.81 | 68.97K |
| 2026-03-04 | Tanguler Tolga | Sell | 289 | $321.82 | 93.01K |
| 2026-03-04 | Tanguler Tolga | Sell | 350 | $323.01 | 113.05K |
| 2026-03-04 | Tanguler Tolga | Sell | 767 | $323.84 | 248.39K |
| 2026-03-04 | Tanguler Tolga | Sell | 272 | $324.88 | 88.37K |
| 2026-03-04 | Tanguler Tolga | Sell | 208 | $325.67 | 67.74K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 29 | $319.03 | 9.25K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 28 | $320.01 | 8.96K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 59 | $320.81 | 18.93K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 79 | $321.82 | 25.42K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 96 | $323.01 | 31.01K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 210 | $323.84 | 68.01K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 75 | $324.88 | 24.37K |
| 2026-03-04 | Fitzgerald Kevin Joseph | Sell | 57 | $325.67 | 18.56K |
| 2026-03-03 | Garg Pushkal | Sell | 355 | $316.74 | 112.44K |
| 2026-03-03 | Garg Pushkal | Sell | 317 | $319.06 | 101.14K |
| 2026-03-03 | Garg Pushkal | Sell | 640 | $320.48 | 205.11K |
| 2026-03-03 | Garg Pushkal | Sell | 463 | $321.50 | 148.85K |
| 2026-03-03 | Fitzgerald Kevin Joseph | Sell | 289 | $316.55 | 91.48K |
Latest filed quarter: Q2 2026.
Institutions holding: 830, holders +2 vs prior quarter. Ownership 100.97%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| FMR LLC | 15.02M | 444.80K | +3.05% | 4.52B |
| CAPITAL WORLD INVESTORS | 11.14M | 342.50K | +3.17% | 3.35B |
| BLACKROCK, INC. | 10.91M | 462.77K | +4.43% | 3.28B |
| CAPITAL RESEARCH GLOBAL INVESTORS | 9.75M | 279.52K | +2.95% | 2.94B |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 6.54M | 47.11K | +0.73% | 1.97B |
| VANGUARD CAPITAL MANAGEMENT LLC | 6.03M | 82.77K | +1.39% | 1.82B |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 5.64M | 448.85K | +8.64% | 1.70B |
| INVESCO LTD. | 3.75M | 970.92K | +34.88% | 1.13B |
| STATE STREET CORP | 3.56M | 232.99K | +7.01% | 1.07B |
| GEODE CAPITAL MANAGEMENT, LLC | 2.64M | -24.55K | -0.92% | 791.35M |
| JPMORGAN CHASE & CO | 2.68M | -3.65M | -57.69% | 785.32M |
| BAILLIE GIFFORD & CO | 2.44M | -53.98K | -2.16% | 734.48M |
| NORGES BANK | 2.27M | 2.27M | New | 683.88M |
| WELLINGTON MANAGEMENT GROUP LLP | 2.11M | 174.48K | +9.01% | 635.30M |
| ORBIS ALLAN GRAY LTD | 1.99M | 652.58K | +48.89% | 598.27M |
| DODGE & COX | 1.96M | 26.14K | +1.35% | 588.63M |
| TWO SIGMA INVESTMENTS, LP | 1.88M | -116.64K | -5.85% | 564.71M |
| AMERICAN CENTURY COMPANIES INC | 1.85M | 51.59K | +2.86% | 558.10M |
| CLEARBRIDGE INVESTMENTS, LLC | 1.26M | -96.55K | -7.12% | 379.14M |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1.15M | -283.55K | -19.79% | 345.94M |
| D. E. SHAW & CO., INC. | 1.10M | 695.31K | +170.09% | 332.37M |
| MORGAN STANLEY | 1.03M | 29.47K | +2.94% | 310.71M |
| BANK OF AMERICA CORP /DE/ | 994.48K | 27.56K | +2.85% | 299.37M |
| LEGAL & GENERAL GROUP PLC | 924.56K | -10.32K | -1.10% | 278.32M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 893.79K | 231.43K | +34.94% | 269.06M |
| Period | Value |
|---|---|
| FY2018 | Product: 12535000.0 |
| FY2019 | Product: 166537000.0 |
| FY2020 | Product: 361520000.0 |
| FY2021 | Product: 662138000.0, Royalty: 1196000.0 |
| FY2022 | Product: 894329000.0, Royalty: 8177000.0 |
| FY2023 | GIVLAARI: 219251000.0, Product: 1241474000.0 |
| FY2024 | GIVLAARI: 255871000.0, Product: 1646228000.0 |
| FY2025 | AMVUTTRA: 2313836000.0, GIVLAARI: 308487000.0, Net revenues from collaborations: 553366000.0, ONPATTRO: 172789000.0, OXLUMO: 191437000.0, Royalty revenue: 174022000.0 |
| Period | Value |
|---|---|
| FY2019 | Non-US Or Europe: 50085000.0, UNITED STATES: 116452000.0 |
| FY2020 | Europe: 333000.0, Non-US Or Europe: 46752000.0, UNITED STATES: 151574000.0 |
| FY2021 | Europe: 38949000.0, Non-US Or Europe: 1761000.0, UNITED STATES: 18876000.0 |
| FY2022 | Europe: 37915000.0, Non-US Or Europe: 4169000.0, UNITED STATES: 27698000.0 |
| FY2023 | Europe: 210916000.0, Non-US Or Europe: 75771000.0, UNITED STATES: 411169000.0 |
| FY2024 | Europe: 235441000.0, Non-US Or Europe: 104396000.0, UNITED STATES: 630613000.0 |
| FY2025 | Europe: 405899000.0, Non-US Or Europe: 176715000.0, UNITED STATES: 1731222000.0 |
Insights · Dividends · Forecast · Financials · Learn
$30.66B
Market Cap
37.32
P/E
35.31
Forward P/E
70
Score