Madrigal Pharmaceuticals (MDGL) Stock Insights
MDGL$431.00-9.33 -2.12%
$9.96B
Market Cap
-33.96
P/E
75.87
Forward P/E
64
Score
Madrigal Pharmaceuticals (MDGL) Stock Insights
MDGL price $431.00 -9.33 -2.12%
- Ticker
- MDGL
- Price
- $431.00
- Change
- -9.33 -2.12%
- Market cap ?
- $9.96B
- P/E ?
- -33.96
- Forward P/E ?
- 75.87
- Dividend yield ?
- 0.00%
- Beta ?
- -1.05
- Sector
- Healthcare
- Industry
- Biotechnology
- Stocklytics score
- 64
- Value
- 48
- Quality
- 44
- Growth
- 100
Stocklytics score rationale: value 48, quality 44, growth 100.
Financials
| 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|
| 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 180133000 | 958403000 |
Madrigal Pharmaceuticals, Inc. is a biopharmaceutical company in the clinical development phase, concentrating its efforts on discovering and commercializing innovative treatments for cardiovascular, metabolic, and liver disorders. Its most advanced drug candidate, resmetirom, functions as a liver-targeted selective thyroid hormone receptor-ß agonist, currently undergoing late-stage (Phase III) clinical trials for…
Fair value
MDGL fair value $309.78. Price $431.00. Price is 39% above fair value.
Fair value is an estimate of what one share is worth if future cash flows arrive as modeled. It is not a forecast of the share price. How discounted cash flow works.
Calculated with a 10-year free-cash-flow discount. Starting free cash flow 250.96M. Growth 20.00%. When analyst earnings forecasts are available, free cash flow in those years is forecast earnings times the company's usual conversion of earnings into free cash flow, kept between 60% and 130%. Years with fewer than 3 analyst estimates are left out. Growth then fades in a straight line to terminal growth by year 10, starting from the last well-covered year's growth, or from the pace across those years when the final year slows sharply, kept between 0% and 20%. Without those forecasts, year-1 growth is analyst revenue growth for the next full fiscal year, or 5-year historical revenue growth when that forecast is missing, held for five years, then fading in a straight line to terminal growth by year 10. Terminal growth 3.00%. Discount rate 10.00%. Beta is kept between 0.8 and 2.0, which on its own would make the discount rate 8.7% to 15.3%. The rate is then capped at 12%. A cap is used because a discount above 12% pushes higher-beta stocks further from the price. The discount rate stays at least 5 percentage points above terminal growth. Shares 23.10M. Net debt 155.67M. The earnings value is next-12-months earnings per share, or trailing earnings when that forecast is missing, times the median P/E of the company's industry. That median uses listed stocks worth at least $10 billion with a positive P/E of 100 or below, and the industry needs at least eight of them. Otherwise the sector median is used when that group also has at least eight, then the market median of those large companies. The multiple used is the lower of that median and 1.25 times the stock's own 10-year median P/E, then kept between 8 and 30. If the stock has no 10-year median, the peer median is kept between 8 and 30. Fair value is the average of the cash-flow value and the earnings value when both exist. Card and credit companies use the earnings value only, because changes in customer receivables distort free cash flow. Model uncertainty is high when fair value is more than 60% from the price, or when most of the cash-flow value sits after year 10.
Earnings
| Date | EPS actual | EPS estimate | Revenue | Revenue estimate |
|---|---|---|---|---|
| 2026-11-03 | — | -0.86 | — | 404.17M |
| 2026-07-30 | -1.99 | -2.68 | 364.30M | 352.13M |
| 2026-05-06 | -3.25 | -3.61 | 311.34M | 301.05M |
| 2026-02-19 | -2.57 | 0.04 | 321.10M | 312.51M |
| 2025-11-04 | -5.08 | -2.04 | 287.27M | 244.96M |
| 2025-08-05 | -1.90 | -3.48 | 212.80M | 243.47M |
| 2025-05-01 | -3.32 | -3.62 | 137.25M | 158.93M |
| 2025-02-26 | -2.71 | -4.32 | 103.32M | 97.81M |
| 2024-10-31 | -4.92 | -6.94 | 62.17M | 92.53M |
| 2024-08-07 | -7.10 | -7.55 | 14.64M | 3.90M |
| 2024-05-07 | -7.38 | -6.06 | — | 3.90M |
| 2024-02-28 | -5.68 | -5.32 | 770.00K | — |
| 2023-11-06 | -5.34 | -4.78 | — | — |
| 2023-08-08 | -4.69 | -4.47 | — | — |
| 2023-05-09 | -4.23 | -4.98 | — | — |
| 2023-02-23 | -4.98 | -4.41 | — | — |
| 2022-11-03 | -4.75 | -4.05 | — | — |
| 2022-08-04 | -4.14 | -3.76 | — | — |
| 2022-05-09 | -3.36 | -3.75 | — | — |
| 2022-02-24 | -3.78 | -3.92 | — | — |
| 2021-11-04 | -3.79 | -3.89 | — | — |
| 2021-08-05 | -3.72 | -3.55 | — | — |
| 2021-05-06 | -3.32 | -3.78 | — | — |
| 2021-02-25 | -3.82 | -3.82 | — | — |
| 2020-11-05 | -3.75 | -3.35 | — | 4.83M |
| 2020-08-06 | -3.18 | -2.42 | — | 4.34M |
| 2020-05-07 | -2.34 | -1.94 | — | — |
| 2020-02-26 | -1.80 | -1.56 | — | 4.62M |
| 2019-11-06 | -1.39 | -1.36 | — | 5.19M |
| 2019-08-07 | -1.28 | -1.08 | — | 6.67M |
| 2019-05-08 | -0.98 | -0.93 | — | 5.69M |
| 2019-02-27 | -0.75 | -0.75 | — | — |
| 2018-11-06 | -0.56 | -0.54 | — | — |
| 2018-08-07 | -0.45 | -0.56 | — | — |
| 2018-05-08 | -0.45 | -0.75 | — | — |
| 2018-03-13 | -0.67 | -0.68 | — | — |
| 2017-11-09 | -0.68 | -0.84 | — | — |
| 2017-08-10 | -0.69 | -0.60 | — | 1.41M |
| 2017-05-11 | -0.50 | -1.39 | — | — |
| 2017-04-03 | -0.67 | — | — | — |
Dividends
Yield 0.00%. Payout ratio 0.00%. Frequency —.
Safety score 37/100 · Watch. Payout ratio is 0% of earnings. Free-cash-flow coverage is not available, so this part stays neutral. No dividend history was found. There is no dividend yield.
| Ex-date | Dividend | Record | Payment | Frequency |
|---|---|---|---|---|
| No data yet. | ||||
Insider trades
| Date | Insider | Action | Shares | Price | Value |
|---|---|---|---|---|---|
| 2026-09-11 | Sibold William John | Sell | 60 | $533.09 | 31.99K |
| 2026-09-11 | Sibold William John | Sell | 106 | $534.06 | 56.61K |
| 2026-09-11 | Sibold William John | Sell | 218 | $535.94 | 116.84K |
| 2026-09-11 | Sibold William John | Sell | 160 | $537.62 | 86.02K |
| 2026-09-11 | Sibold William John | Sell | 687 | $540.59 | 371.38K |
| 2026-09-11 | Sibold William John | Sell | 368 | $541.64 | 199.32K |
| 2026-09-11 | Sibold William John | Sell | 1.20K | $542.60 | 652.21K |
| 2026-09-11 | Sibold William John | Sell | 1.54K | $544.02 | 837.25K |
| 2026-09-11 | Sibold William John | Sell | 761 | $544.83 | 414.62K |
| 2026-09-11 | Sibold William John | Sell | 120 | $546.38 | 65.57K |
| 2026-09-09 | Sibold William John | Sell | 131 | $527.88 | 69.15K |
| 2026-09-09 | Sibold William John | Sell | 347 | $529.27 | 183.66K |
| 2026-09-09 | Sibold William John | Sell | 522 | $530.23 | 276.78K |
| 2026-09-09 | Sibold William John | Sell | 368 | $531.99 | 195.77K |
| 2026-09-09 | Sibold William John | Sell | 512 | $533.09 | 272.94K |
| 2026-09-09 | Sibold William John | Sell | 396 | $534.20 | 211.54K |
| 2026-09-09 | Sibold William John | Sell | 644 | $535.27 | 344.72K |
| 2026-09-09 | Sibold William John | Sell | 1.04K | $536.11 | 557.56K |
| 2026-09-09 | Sibold William John | Sell | 640 | $537.17 | 343.79K |
| 2026-09-09 | Sibold William John | Sell | 520 | $538.30 | 279.91K |
| 2026-09-09 | Sibold William John | Sell | 215 | $539.03 | 115.89K |
| 2026-09-09 | Sibold William John | Sell | 505 | $540.19 | 272.80K |
| 2026-09-09 | Sibold William John | Sell | 362 | $541.65 | 196.08K |
| 2026-09-09 | Sibold William John | Sell | 160 | $542.55 | 86.81K |
| 2026-08-17 | Kelley Shannon T | Sell | 664 | $514.97 | 341.94K |
| 2026-08-15 | REED JOHN C | Buy | 1.08K | $507.56 | 547.15K |
| 2026-08-15 | REED JOHN C | Buy | 647 | — | — |
| 2026-08-11 | REED JOHN C | Other | 0 | — | — |
| 2026-07-20 | Sibold William John | Sell | 140 | $542.75 | 75.98K |
| 2026-07-20 | Sibold William John | Sell | 110 | $543.79 | 59.82K |
| 2026-07-20 | Sibold William John | Sell | 545 | $544.71 | 296.87K |
| 2026-07-20 | Sibold William John | Sell | 275 | $545.71 | 150.07K |
| 2026-07-20 | Sibold William John | Sell | 269 | $547.08 | 147.16K |
| 2026-07-20 | Sibold William John | Sell | 680 | $547.70 | 372.43K |
| 2026-07-20 | Sibold William John | Sell | 47 | $548.87 | 25.80K |
| 2026-07-20 | Sibold William John | Sell | 153 | $550.01 | 84.15K |
| 2026-07-20 | Sibold William John | Sell | 1 | $550.72 | 551 |
| 2026-07-20 | Sibold William John | Sell | 280 | $555.05 | 155.41K |
| 2026-07-17 | Sibold William John | Buy | 50.00K | — | — |
| 2026-07-17 | Sibold William John | Sell | 50.00K | — | — |
| 2026-06-17 | Taub Rebecca | Buy | 454 | — | — |
| 2026-06-17 | Taub Rebecca | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | Levy Richard S | Buy | 454 | — | — |
| 2026-06-17 | Levy Richard S | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | FOUSE JACQUALYN A | Buy | 454 | — | — |
| 2026-06-17 | FOUSE JACQUALYN A | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | Daly James M | Buy | 454 | — | — |
| 2026-06-17 | Daly James M | Buy | 766 | $499.86 | 382.89K |
| 2026-06-17 | Brennan Daniel J. | Buy | 404 | — | — |
| 2026-06-17 | Brennan Daniel J. | Buy | 681 | $499.86 | 340.40K |
| 2026-06-17 | BAKER BROS. ADVISORS LP | Buy | 908 | — | — |
| 2026-06-17 | BAKER BROS. ADVISORS LP | Buy | 908 | — | — |
| 2026-06-17 | BAKER BROS. ADVISORS LP | Buy | 1.53K | $499.86 | 765.79K |
| 2026-06-01 | Soergel David | Sell | 1.04K | $495.74 | 516.56K |
| 2026-05-22 | Levy Richard S | Sell | 40 | $506.68 | 20.27K |
| 2026-05-22 | Levy Richard S | Sell | 320 | $508.24 | 162.64K |
| 2026-05-22 | Levy Richard S | Sell | 151 | $510.36 | 77.06K |
| 2026-05-22 | Levy Richard S | Sell | 610 | $511.40 | 311.95K |
| 2026-05-22 | Levy Richard S | Sell | 439 | $512.50 | 224.99K |
| 2026-05-22 | Levy Richard S | Sell | 40 | $512.97 | 20.52K |
| 2026-05-22 | Levy Richard S | Sell | 343 | $514.67 | 176.53K |
| 2026-05-22 | Levy Richard S | Sell | 657 | $515.92 | 338.96K |
| 2026-05-22 | Levy Richard S | Sell | 723 | $516.87 | 373.69K |
| 2026-05-22 | Levy Richard S | Sell | 1.50K | $517.59 | 774.84K |
| 2026-05-22 | Levy Richard S | Sell | 782 | $518.76 | 405.67K |
| 2026-05-22 | Levy Richard S | Sell | 80 | $519.98 | 41.60K |
| 2026-05-18 | Soergel David | Sell | 844 | $515.90 | 435.42K |
| 2026-03-06 | Dier Mardi | Sell | 646 | $431.94 | 279.03K |
| 2026-03-06 | Dier Mardi | Sell | 40 | $425.08 | 17.00K |
| 2026-03-06 | Dier Mardi | Sell | 420 | $426.86 | 179.28K |
| 2026-03-06 | Dier Mardi | Sell | 80 | $427.85 | 34.23K |
| 2026-03-06 | Dier Mardi | Sell | 160 | $429.00 | 68.64K |
| 2026-03-06 | Dier Mardi | Sell | 40 | $429.58 | 17.18K |
| 2026-03-06 | Dier Mardi | Sell | 120 | $430.90 | 51.71K |
| 2026-03-06 | Dier Mardi | Sell | 116 | $432.56 | 50.18K |
| 2026-03-06 | Dier Mardi | Sell | 160 | $434.20 | 69.47K |
| 2026-03-06 | Dier Mardi | Sell | 80 | $435.31 | 34.83K |
| 2026-03-06 | Dier Mardi | Sell | 80 | $436.69 | 34.94K |
| 2026-03-06 | Dier Mardi | Sell | 40 | $437.65 | 17.51K |
| 2026-03-06 | Sibold William John | Sell | 1.66K | $431.94 | 718.32K |
| 2026-03-06 | Kelley Shannon T | Sell | 360 | $431.94 | 155.50K |
| 2026-03-06 | Huntsman Carole | Sell | 419 | $431.94 | 180.98K |
| 2026-03-06 | Taub Rebecca | Sell | 491 | $431.94 | 212.08K |
| 2026-03-04 | Dier Mardi | Buy | 5.21K | — | — |
| 2026-03-04 | Dier Mardi | Buy | 6.52K | $434.80 | 2.83M |
| 2026-03-04 | Sibold William John | Buy | 14.99K | — | — |
| 2026-03-04 | Sibold William John | Buy | 18.74K | $434.80 | 8.15M |
| 2026-03-04 | Kelley Shannon T | Buy | 4.02K | — | — |
| 2026-03-04 | Kelley Shannon T | Buy | 5.02K | $434.80 | 2.18M |
| 2026-03-04 | Huntsman Carole | Buy | 3.99K | — | — |
| 2026-03-04 | Huntsman Carole | Buy | 4.99K | $434.80 | 2.17M |
| 2026-03-04 | Soergel David | Buy | 4.37K | — | — |
| 2026-03-04 | Soergel David | Buy | 5.47K | $434.80 | 2.38M |
| 2026-03-02 | Dier Mardi | Sell | 1.18K | $427.21 | 505.39K |
| 2026-02-23 | Levy Richard S | Buy | 2.50K | $7.36 | 18.40K |
| 2026-02-23 | Levy Richard S | Sell | 2.50K | $7.36 | 18.40K |
| 2026-01-26 | Levy Richard S | Buy | 4.00K | $16.46 | 65.84K |
| 2026-01-26 | Levy Richard S | Sell | 4.00K | $16.46 | 65.84K |
| 2026-01-26 | Huntsman Carole | Sell | 340 | $492.42 | 167.42K |
| 2026-01-26 | Huntsman Carole | Sell | 570 | $494.59 | 281.92K |
Institutional holders
Latest filed quarter: Q2 2026.
Institutions holding: 439, holders +31 vs prior quarter. Ownership 81.57%.
| Holder | Shares | Change | Change % | Value |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 2.14M | 1.43K | +0.07% | 1.15B |
| RTW INVESTMENTS, LP | 1.99M | 0 | 0.00% | 1.07B |
| JUPITER TOPCO LLC | 1.94M | 1.94M | New | 1.04B |
| AVORO CAPITAL ADVISORS LLC | 1.83M | 15.15K | +0.83% | 984.41M |
| PAULSON & CO. INC. | 1.34M | -52.17K | -3.75% | 719.52M |
| BLACKROCK, INC. | 1.20M | -359.19K | -23.03% | 644.75M |
| VANGUARD CAPITAL MANAGEMENT LLC | 835.67K | 8.52K | +1.03% | 448.71M |
| WELLINGTON MANAGEMENT GROUP LLP | 825.71K | 130.76K | +18.81% | 443.37M |
| VANGUARD PORTFOLIO MANAGEMENT LLC | 781.73K | -59.41K | -7.06% | 419.75M |
| STATE STREET CORP | 527.06K | -82.47K | -13.53% | 283.00M |
| CITADEL ADVISORS LLC | 507.23K | 470.93K | +1297.34% | 272.36M |
| UBS GROUP AG | 401.71K | 283.93K | +241.07% | 215.70M |
| GEODE CAPITAL MANAGEMENT, LLC | 374.88K | -80.99K | -17.77% | 201.34M |
| FMR LLC | 356.20K | -155.53K | -30.39% | 191.26M |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 324.12K | -16.40K | -4.82% | 174.04M |
| INVESCO LTD. | 301.44K | -28.08K | -8.52% | 161.86M |
| ARMISTICE CAPITAL, LLC | 288.00K | 23.42K | +8.85% | 154.64M |
| LORD, ABBETT & CO. LLC | 281.50K | 38.77K | +15.97% | 151.15M |
| GOLDMAN SACHS GROUP INC | 246.28K | -31.09K | -11.21% | 132.24M |
| POLAR CAPITAL HOLDINGS PLC | 244.27K | -45.04K | -15.57% | 131.16M |
| AMERIPRISE FINANCIAL INC | 231.21K | 133.02K | +135.49% | 124.15M |
| NORGES BANK | 213.89K | 213.89K | New | 114.85M |
| ARTISAN PARTNERS LIMITED PARTNERSHIP | 210.21K | 26.66K | +14.53% | 112.87M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 209.80K | 187.58K | +844.36% | 112.65M |
| PICTET ASSET MANAGEMENT HOLDING SA | 192.90K | 5.66K | +3.02% | 103.49M |
Insights
- Revenue by product
| Period | Value |
|---|---|
| FY2025 | Reportable Segment: 958403000.0 |
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